Impaired cardiac autonomic nervous control after cardiac bypass surgery for congenital heart disease

Laura McGlone, Neil Patel, David Young, Mark D. Danton, Financial Support Department of Cardiac Surgery and Cardiology, The Royal Hospital for Sick Children, Yorkhill, Glasgow (Funder)

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We undertook a study to describe changes in heart rate variability (HRV) postoperatively in children undergoing cardiac bypass surgery for congenital heart disease (CHD). HRV was recorded for a 1-h period preoperatively and a 24-h period postoperatively in 20 children with CHD. We found a highly significant reduction in HRV in both time and frequency domain indices compared to preoperative values, which was sustained throughout the 24-h study period. There was a negative correlation between both time and frequency domain HRV measurements and length of cardiac bypass. HRV is reduced postoperatively and correlates with cardiac bypass time. Length of cardiac bypass time may be one mechanism whereby HRV is reduced following surgery.
Original languageEnglish
Pages (from-to)218-222
Number of pages4
JournalInteractive Cardiovascular and Thoracic Surgery
Issue number2
Publication statusPublished - May 2009


  • cardiopulmonary bypass
  • congenital
  • autonomic nervous system
  • heart rate

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