Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial

C.A. Donnelly, G. Wei, W.T. Johnston, D.R. Cox, R. Woodroffe, F.J. Bourne, C.L. Cheeseman, R. Clifton-Hadley, G. Gettinby

Research output: Contribution to journalArticle

81 Citations (Scopus)

Abstract

Bovine tuberculosis (TB) has re-emerged as a major problem for British cattle farmers. Failure to control the infection has been linked to transmission from European badgers; badger culling has therefore formed a component of British TB control policy since 1973. To investigate the impact of repeated widespread badger culling on cattle TB, the Randomised Badger Culling Trial compared TB incidence in cattle herds in and around ten culling areas (each 100 km2) with those in and around ten matched unculled areas. Overall, cattle TB incidence was 23.2% lower (95% confidence interval (CI) 12.4-32.7% lower) inside culled areas, but 24.5% (95% CI 0.6% lower-56.0% higher) higher on land ≤2 km outside, relative to matched unculled areas. Inside the culling area boundary the beneficial effect of culling tended to increase with distance from the boundary (p = 0.085) and to increase on successive annual culls (p = 0.064). In adjoining areas, the detrimental effect tended to diminish on successive annual culls (p = 0.17). On the basis of such linear trends, the estimated net effect per annum for culling areas similar to those in the trial was detrimental between the first and second culls, but beneficial after the fourth and later culls, for the range of analyses performed. Careful consideration is needed to determine in what settings systematic repeated culling might be reliably predicted to be beneficial, and in these cases whether the benefits of such culling warrant the costs involved.
LanguageEnglish
Pages300-308
Number of pages8
JournalInternational Journal of Infectious Diseases
Volume11
Issue number4
DOIs
Publication statusPublished - Jul 2007

Fingerprint

Mustelidae
Tuberculosis
Confidence Intervals
Bovine Tuberculosis
Incidence
Infection Control
Costs and Cost Analysis

Keywords

  • bovine TB
  • Mycobacterium bovis
  • badger culling
  • cattle
  • tuberculosis

Cite this

Donnelly, C.A. ; Wei, G. ; Johnston, W.T. ; Cox, D.R. ; Woodroffe, R. ; Bourne, F.J. ; Cheeseman, C.L. ; Clifton-Hadley, R. ; Gettinby, G. / Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial. In: International Journal of Infectious Diseases. 2007 ; Vol. 11, No. 4. pp. 300-308.
@article{8536eeec5c2945c7817eca3501f028f0,
title = "Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial",
abstract = "Bovine tuberculosis (TB) has re-emerged as a major problem for British cattle farmers. Failure to control the infection has been linked to transmission from European badgers; badger culling has therefore formed a component of British TB control policy since 1973. To investigate the impact of repeated widespread badger culling on cattle TB, the Randomised Badger Culling Trial compared TB incidence in cattle herds in and around ten culling areas (each 100 km2) with those in and around ten matched unculled areas. Overall, cattle TB incidence was 23.2{\%} lower (95{\%} confidence interval (CI) 12.4-32.7{\%} lower) inside culled areas, but 24.5{\%} (95{\%} CI 0.6{\%} lower-56.0{\%} higher) higher on land ≤2 km outside, relative to matched unculled areas. Inside the culling area boundary the beneficial effect of culling tended to increase with distance from the boundary (p = 0.085) and to increase on successive annual culls (p = 0.064). In adjoining areas, the detrimental effect tended to diminish on successive annual culls (p = 0.17). On the basis of such linear trends, the estimated net effect per annum for culling areas similar to those in the trial was detrimental between the first and second culls, but beneficial after the fourth and later culls, for the range of analyses performed. Careful consideration is needed to determine in what settings systematic repeated culling might be reliably predicted to be beneficial, and in these cases whether the benefits of such culling warrant the costs involved.",
keywords = "bovine TB, Mycobacterium bovis, badger culling, cattle, tuberculosis",
author = "C.A. Donnelly and G. Wei and W.T. Johnston and D.R. Cox and R. Woodroffe and F.J. Bourne and C.L. Cheeseman and R. Clifton-Hadley and G. Gettinby",
note = "Strathprints' policy is to record up to 8 authors per publication, plus any additional authors based at the University of Strathclyde. More authors may be listed on the official publication than appear in the Strathprints' record.",
year = "2007",
month = "7",
doi = "10.1016/j.ijid.2007.04.001",
language = "English",
volume = "11",
pages = "300--308",
journal = "International Journal of Infectious Diseases",
issn = "1201-9712",
number = "4",

}

Donnelly, CA, Wei, G, Johnston, WT, Cox, DR, Woodroffe, R, Bourne, FJ, Cheeseman, CL, Clifton-Hadley, R & Gettinby, G 2007, 'Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial' International Journal of Infectious Diseases, vol. 11, no. 4, pp. 300-308. https://doi.org/10.1016/j.ijid.2007.04.001

Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial. / Donnelly, C.A.; Wei, G.; Johnston, W.T.; Cox, D.R.; Woodroffe, R.; Bourne, F.J.; Cheeseman, C.L.; Clifton-Hadley, R.; Gettinby, G.

In: International Journal of Infectious Diseases, Vol. 11, No. 4, 07.2007, p. 300-308.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Impacts of widespread badger culling on cattle tuberculosis: concluding analyses from a large-scale field trial

AU - Donnelly, C.A.

AU - Wei, G.

AU - Johnston, W.T.

AU - Cox, D.R.

AU - Woodroffe, R.

AU - Bourne, F.J.

AU - Cheeseman, C.L.

AU - Clifton-Hadley, R.

AU - Gettinby, G.

N1 - Strathprints' policy is to record up to 8 authors per publication, plus any additional authors based at the University of Strathclyde. More authors may be listed on the official publication than appear in the Strathprints' record.

PY - 2007/7

Y1 - 2007/7

N2 - Bovine tuberculosis (TB) has re-emerged as a major problem for British cattle farmers. Failure to control the infection has been linked to transmission from European badgers; badger culling has therefore formed a component of British TB control policy since 1973. To investigate the impact of repeated widespread badger culling on cattle TB, the Randomised Badger Culling Trial compared TB incidence in cattle herds in and around ten culling areas (each 100 km2) with those in and around ten matched unculled areas. Overall, cattle TB incidence was 23.2% lower (95% confidence interval (CI) 12.4-32.7% lower) inside culled areas, but 24.5% (95% CI 0.6% lower-56.0% higher) higher on land ≤2 km outside, relative to matched unculled areas. Inside the culling area boundary the beneficial effect of culling tended to increase with distance from the boundary (p = 0.085) and to increase on successive annual culls (p = 0.064). In adjoining areas, the detrimental effect tended to diminish on successive annual culls (p = 0.17). On the basis of such linear trends, the estimated net effect per annum for culling areas similar to those in the trial was detrimental between the first and second culls, but beneficial after the fourth and later culls, for the range of analyses performed. Careful consideration is needed to determine in what settings systematic repeated culling might be reliably predicted to be beneficial, and in these cases whether the benefits of such culling warrant the costs involved.

AB - Bovine tuberculosis (TB) has re-emerged as a major problem for British cattle farmers. Failure to control the infection has been linked to transmission from European badgers; badger culling has therefore formed a component of British TB control policy since 1973. To investigate the impact of repeated widespread badger culling on cattle TB, the Randomised Badger Culling Trial compared TB incidence in cattle herds in and around ten culling areas (each 100 km2) with those in and around ten matched unculled areas. Overall, cattle TB incidence was 23.2% lower (95% confidence interval (CI) 12.4-32.7% lower) inside culled areas, but 24.5% (95% CI 0.6% lower-56.0% higher) higher on land ≤2 km outside, relative to matched unculled areas. Inside the culling area boundary the beneficial effect of culling tended to increase with distance from the boundary (p = 0.085) and to increase on successive annual culls (p = 0.064). In adjoining areas, the detrimental effect tended to diminish on successive annual culls (p = 0.17). On the basis of such linear trends, the estimated net effect per annum for culling areas similar to those in the trial was detrimental between the first and second culls, but beneficial after the fourth and later culls, for the range of analyses performed. Careful consideration is needed to determine in what settings systematic repeated culling might be reliably predicted to be beneficial, and in these cases whether the benefits of such culling warrant the costs involved.

KW - bovine TB

KW - Mycobacterium bovis

KW - badger culling

KW - cattle

KW - tuberculosis

UR - http://dx.doi.org/10.1016/j.ijid.2007.04.001

U2 - 10.1016/j.ijid.2007.04.001

DO - 10.1016/j.ijid.2007.04.001

M3 - Article

VL - 11

SP - 300

EP - 308

JO - International Journal of Infectious Diseases

T2 - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

SN - 1201-9712

IS - 4

ER -