Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 1700-1708 |
| Number of pages | 8 |
| Journal | Journal of Materials Research |
| Volume | 24 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2009 |
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Keywords
- imidazole catalyzed silica synthesis
- histidine
- (bio)silicification
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Imidazole catalyzed silica synthesis: Progress toward understanding the role of histidine in (bio)silicification. / Patwardhan, Siddharth V.
In: Journal of Materials Research, Vol. 24, No. 4, 2009, p. 1700-1708.Research output: Contribution to journal › Article
TY - JOUR
T1 - Imidazole catalyzed silica synthesis: Progress toward understanding the role of histidine in (bio)silicification
AU - Patwardhan, Siddharth V
PY - 2009
Y1 - 2009
N2 - Histidine is an amino acid present in proteins involved in biosilica formation and often found in peptides identified during phage display studies but its role(s) and the extent of its involvement in the silica precipitation process is not fully understood. In this contribution we describe results from an in vitro silicification study conducted using poly-histidine (P-His) and a series of different molecular weight synthetic polymers containing the imidazole functionality (polyvinyl imidazole, PVI) for comparison. We show that the presence of imidazole from PVI or P-His is able to catalyze silicic acid condensation; the effect being greater for P-His. The catalytic mechanism is proposed to involve the dual features of the imidazole group-its ability to form hydrogen bonds with silicic acid and electrostatic attraction toward oligomeric silicic acid species.
AB - Histidine is an amino acid present in proteins involved in biosilica formation and often found in peptides identified during phage display studies but its role(s) and the extent of its involvement in the silica precipitation process is not fully understood. In this contribution we describe results from an in vitro silicification study conducted using poly-histidine (P-His) and a series of different molecular weight synthetic polymers containing the imidazole functionality (polyvinyl imidazole, PVI) for comparison. We show that the presence of imidazole from PVI or P-His is able to catalyze silicic acid condensation; the effect being greater for P-His. The catalytic mechanism is proposed to involve the dual features of the imidazole group-its ability to form hydrogen bonds with silicic acid and electrostatic attraction toward oligomeric silicic acid species.
KW - imidazole catalyzed silica synthesis
KW - histidine
KW - (bio)silicification
UR - http://dx.doi.org/10.1557/JMR.2009.0223
U2 - 10.1557/JMR.2009.0223
DO - 10.1557/JMR.2009.0223
M3 - Article
VL - 24
SP - 1700
EP - 1708
JO - Journal of Materials Research
JF - Journal of Materials Research
SN - 0884-2914
IS - 4
ER -