Images in cardiovascular medicine: multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery

Pasquale Maffia; Bernd H. Zinselmeyer; Armando Ialenti; Simon Kennedy; Andrew H. Baker; Iain B. McInnes; James M. Brewer; Paul Garside

doi:10.1161/CIRCULATIONAHA.106.658492

Images in cardiovascular medicine: multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery

Pasquale Maffia, Bernd H. Zinselmeyer, Armando Ialenti, Simon Kennedy, Andrew H. Baker, Iain B. McInnes, James M. Brewer, Paul Garside

Strathclyde Institute Of Pharmacy And Biomedical Sciences

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Abstract

Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial lymphoid-like tissues.1,2 These results suggest that lymphocyte responses in the
lamina adventitia may play a crucial role in atherosclerosis development.1,2

Original language	English
Pages (from-to)	e326-e328
Number of pages	3
Journal	Circulation
Volume	115
Issue number	11
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.106.658492
Publication status	Published - 20 Mar 2007

Keywords

circulation
cardiovascular
multiphoton microscopy

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Maffia, P., Zinselmeyer, B. H., Ialenti, A., Kennedy, S., Baker, A. H., McInnes, I. B., Brewer, J. M., & Garside, P. (2007). Images in cardiovascular medicine: multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery. Circulation, 115(11), e326-e328. https://doi.org/10.1161/CIRCULATIONAHA.106.658492

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abstract = "Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial lymphoid-like tissues.1,2 These results suggest that lymphocyte responses in thelamina adventitia may play a crucial role in atherosclerosis development.1,2",

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doi = "10.1161/CIRCULATIONAHA.106.658492",

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Maffia, P, Zinselmeyer, BH, Ialenti, A, Kennedy, S, Baker, AH, McInnes, IB, Brewer, JM & Garside, P 2007, 'Images in cardiovascular medicine: multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery', Circulation, vol. 115, no. 11, pp. e326-e328. https://doi.org/10.1161/CIRCULATIONAHA.106.658492

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T1 - Images in cardiovascular medicine

T2 - multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery

AU - Maffia, Pasquale

AU - Zinselmeyer, Bernd H.

AU - Ialenti, Armando

AU - Kennedy, Simon

AU - Baker, Andrew H.

AU - McInnes, Iain B.

AU - Brewer, James M.

AU - Garside, Paul

PY - 2007/3/20

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N2 - Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial lymphoid-like tissues.1,2 These results suggest that lymphocyte responses in thelamina adventitia may play a crucial role in atherosclerosis development.1,2

AB - Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial lymphoid-like tissues.1,2 These results suggest that lymphocyte responses in thelamina adventitia may play a crucial role in atherosclerosis development.1,2

KW - circulation

KW - cardiovascular

KW - multiphoton microscopy

U2 - 10.1161/CIRCULATIONAHA.106.658492

DO - 10.1161/CIRCULATIONAHA.106.658492

M3 - Article

SN - 0009-7322

VL - 115

SP - e326-e328

JO - Circulation

JF - Circulation

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Images in cardiovascular medicine: multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery

Abstract

Keywords

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