Images in cardiovascular medicine: multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery

Pasquale Maffia, Bernd H. Zinselmeyer, Armando Ialenti, Simon Kennedy, Andrew H. Baker, Iain B. McInnes, James M. Brewer, Paul Garside

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)
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Abstract

Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial lymphoid-like tissues.1,2 These results suggest that lymphocyte responses in the
lamina adventitia may play a crucial role in atherosclerosis development.1,2
Original languageEnglish
Pages (from-to)e326-e328
Number of pages3
JournalCirculation
Volume115
Issue number11
DOIs
Publication statusPublished - 20 Mar 2007

Keywords

  • circulation
  • cardiovascular
  • multiphoton microscopy

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