Identifying the operating space and repeatability of a novel filament free FDM printer

Elke Prasad; John Robertson; Gavin W. Halbert

Identifying the operating space and repeatability of a novel filament free FDM printer

Elke Prasad, John Robertson, Gavin W. Halbert

Research output: Contribution to conference › Poster › peer-review

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Abstract

Purpose -- Processing solid dispersion filament feedstock materials by Fused Deposition Modelling (FDM) have shown to facilitate control of drug release profiles through micro-structure design. The mechanical and rheological properties of many feedstock materials, particularly immediate release polymers, are not suitable for processing in a conventional FDM 3D printer. This study shows the operational space and performance of a novel non-filament based FDM printer, overcoming these material-based limitations.

Conclusions -- Operational limits, in terms of rheological properties of formulations, have been identified for this novel non-filament FDM printer. Repeatability of tablet prints showed good uniformity of mass, complying with pharmacopeial specifications for oral solid dose forms.

Original language	English
Publication status	Published - 16 Oct 2022
Event	AAPS 2022 Pharm Sci 360 - USA, Boston, United States Duration: 16 Oct 2022 → 19 Oct 2022 https://www.aaps.org/pharmsci/annual-meeting

Conference

Conference	AAPS 2022 Pharm Sci 360
Country/Territory	United States
City	Boston
Period	16/10/22 → 19/10/22
Internet address	https://www.aaps.org/pharmsci/annual-meeting

Keywords

Fused Deposition Modelling (FDM)
3D printing

Access to Document

Prasad-etal-AAPS-2022-Identifying-the-operating-space-and-repeatability-of-a-novel-filament-free-FDM-printerFinal published version, 685 KBLicence: CC BY 4.0

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Future Continuous Manufacturing and Advanced Crystallisation Research Hub (CMAC Hub)
Florence, A., Brown, C., Halbert, G., Johnston, B., Markl, D., Nordon, A., Price, C. J., Sefcik, J. & Ter Horst, J.
EPSRC (Engineering and Physical Sciences Research Council)
1/01/17 → 30/09/24
Project: Research
Cancer Research UK Formulation - PhD Studentship
Halbert, G., Dick, L., Elliott, M. & Ford, S.
Cancer Research UK CRUK
1/10/15 → 31/03/22
Project: Research - Studentship

Cite this

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title = "Identifying the operating space and repeatability of a novel filament free FDM printer",

abstract = "Purpose -- Processing solid dispersion filament feedstock materials by Fused Deposition Modelling (FDM) have shown to facilitate control of drug release profiles through micro-structure design. The mechanical and rheological properties of many feedstock materials, particularly immediate release polymers, are not suitable for processing in a conventional FDM 3D printer. This study shows the operational space and performance of a novel non-filament based FDM printer, overcoming these material-based limitations. Conclusions -- Operational limits, in terms of rheological properties of formulations, have been identified for this novel non-filament FDM printer. Repeatability of tablet prints showed good uniformity of mass, complying with pharmacopeial specifications for oral solid dose forms.",

keywords = "Fused Deposition Modelling (FDM), 3D printing",

author = "Elke Prasad and John Robertson and Halbert, {Gavin W.}",

year = "2022",

month = oct,

day = "16",

language = "English",

note = "AAPS 2022 Pharm Sci 360 ; Conference date: 16-10-2022 Through 19-10-2022",

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TY - CONF

T1 - Identifying the operating space and repeatability of a novel filament free FDM printer

AU - Prasad, Elke

AU - Robertson, John

AU - Halbert, Gavin W.

PY - 2022/10/16

Y1 - 2022/10/16

N2 - Purpose -- Processing solid dispersion filament feedstock materials by Fused Deposition Modelling (FDM) have shown to facilitate control of drug release profiles through micro-structure design. The mechanical and rheological properties of many feedstock materials, particularly immediate release polymers, are not suitable for processing in a conventional FDM 3D printer. This study shows the operational space and performance of a novel non-filament based FDM printer, overcoming these material-based limitations. Conclusions -- Operational limits, in terms of rheological properties of formulations, have been identified for this novel non-filament FDM printer. Repeatability of tablet prints showed good uniformity of mass, complying with pharmacopeial specifications for oral solid dose forms.

AB - Purpose -- Processing solid dispersion filament feedstock materials by Fused Deposition Modelling (FDM) have shown to facilitate control of drug release profiles through micro-structure design. The mechanical and rheological properties of many feedstock materials, particularly immediate release polymers, are not suitable for processing in a conventional FDM 3D printer. This study shows the operational space and performance of a novel non-filament based FDM printer, overcoming these material-based limitations. Conclusions -- Operational limits, in terms of rheological properties of formulations, have been identified for this novel non-filament FDM printer. Repeatability of tablet prints showed good uniformity of mass, complying with pharmacopeial specifications for oral solid dose forms.

KW - Fused Deposition Modelling (FDM)

KW - 3D printing

M3 - Poster

T2 - AAPS 2022 Pharm Sci 360

Y2 - 16 October 2022 through 19 October 2022

ER -

Identifying the operating space and repeatability of a novel filament free FDM printer

Abstract

Conference

Keywords

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Projects

Future Continuous Manufacturing and Advanced Crystallisation Research Hub (CMAC Hub)

Cancer Research UK Formulation - PhD Studentship

Cite this