Herein we present a range of substrates that undergo hydrogen isotope exchange with an iridium(I) NHC/phosphine complex bearing the less coordinating tetrakis[3,5-bis(trifluoromethyl)phenyl]borate counterion, and compare these with labelling using the equivalent, more established hexafluorophosphate complex. The changes in reactivity and selectivity of these complexes in a series of solvents are examined.
|Number of pages||4|
|Journal||Journal of Labelled Compounds and Radiopharmaceuticals|
|Early online date||27 Jul 2016|
|Publication status||Published - 31 Dec 2016|
- ortho-hydrogen isotope exchange
- N-heterocyclic carbene