Hydrochlorothiazide N,N-dimethylacetamide disolvate

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Hydrochlorothiazide forms a 1: 2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro- 3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethylacetamide disolvate), C(7)H(8)ClN(3)O(4)S(2)(.)2C(4)H(9)NO. The compound crystallizes with one hydrochorothiazide and two disordered solvent molecules in the asymmetric unit, with a hydrogen-bonding network comprising four N-H (...) O contacts.

Original languageEnglish
Pages (from-to)O2926-O2928
Number of pages3
JournalActa Crystallographica Section E: Structure Reports
Volume62
DOIs
Publication statusPublished - Jul 2006

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Hydrochlorothiazide
dioxides
Hydrogen bonds
Molecules
hydrogen
molecules
dimethylacetamide
Sulfonamides

Keywords

  • crystal structures
  • powder
  • disolvates
  • hydrochlorothiazide

Cite this

@article{ed99a631ba66481f8a25990c00f3b285,
title = "Hydrochlorothiazide N,N-dimethylacetamide disolvate",
abstract = "Hydrochlorothiazide forms a 1: 2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro- 3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethylacetamide disolvate), C(7)H(8)ClN(3)O(4)S(2)(.)2C(4)H(9)NO. The compound crystallizes with one hydrochorothiazide and two disordered solvent molecules in the asymmetric unit, with a hydrogen-bonding network comprising four N-H (...) O contacts.",
keywords = "crystal structures, powder, disolvates, hydrochlorothiazide",
author = "Andrea Johnston and Florence, {Alastair J.} and Kennedy, {Alan R.}",
year = "2006",
month = "7",
doi = "10.1017/S160056806022859",
language = "English",
volume = "62",
pages = "O2926--O2928",
journal = "Acta Crystallographica Section E: Structure Reports",
issn = "1600-5368",

}

Hydrochlorothiazide N,N-dimethylacetamide disolvate. / Johnston, Andrea; Florence, Alastair J.; Kennedy, Alan R.

In: Acta Crystallographica Section E: Structure Reports, Vol. 62, 07.2006, p. O2926-O2928.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Hydrochlorothiazide N,N-dimethylacetamide disolvate

AU - Johnston, Andrea

AU - Florence, Alastair J.

AU - Kennedy, Alan R.

PY - 2006/7

Y1 - 2006/7

N2 - Hydrochlorothiazide forms a 1: 2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro- 3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethylacetamide disolvate), C(7)H(8)ClN(3)O(4)S(2)(.)2C(4)H(9)NO. The compound crystallizes with one hydrochorothiazide and two disordered solvent molecules in the asymmetric unit, with a hydrogen-bonding network comprising four N-H (...) O contacts.

AB - Hydrochlorothiazide forms a 1: 2 solvate with N,N-dimethylacetamide (systematic name: 6-chloro- 3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide dimethylacetamide disolvate), C(7)H(8)ClN(3)O(4)S(2)(.)2C(4)H(9)NO. The compound crystallizes with one hydrochorothiazide and two disordered solvent molecules in the asymmetric unit, with a hydrogen-bonding network comprising four N-H (...) O contacts.

KW - crystal structures

KW - powder

KW - disolvates

KW - hydrochlorothiazide

U2 - 10.1017/S160056806022859

DO - 10.1017/S160056806022859

M3 - Article

VL - 62

SP - O2926-O2928

JO - Acta Crystallographica Section E: Structure Reports

JF - Acta Crystallographica Section E: Structure Reports

SN - 1600-5368

ER -