Hybrid organic semiconductor lasers for bio-molecular sensing

Anne-Marie Haughey, Caroline Foucher, Benoit Guilhabert, Alexander L. Kanibolotsky, Peter J. Skabara, Glenn Burley, Martin D. Dawson, Nicolas Laurand

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Bio-functionalised luminescent organic semiconductors are attractive for biophotonics because they can act as efficient laser materials while simultaneously interacting with molecules. In this paper, we present and discuss a laser biosensor platform that utilises a gain layer made of such an organic semiconductor material. The simple structure of the sensor and its operation principle are described. Nanolayer detection is shown experimentally and analysed theoretically in order to assess the potential and the limits of the biosensor. The advantage conferred by the organic semiconductor is explained, and comparisons to laser sensors using alternative dye-doped materials are made. Specific biomolecular sensing is demonstrated, and routes to functionalisation with nucleic acid probes, and future developments opened up by this achievement, are highlighted. Finally, attractive formats for sensing applications are mentioned, as well as colloidal quantum dots, which in the future could be used in conjunction with organic semiconductors.

Original languageEnglish
Pages (from-to)369-381
Number of pages13
JournalFaraday Discussions
Early online date27 May 2014
Publication statusPublished - 2014


  • bio-functionalised luminescent organic semiconductors
  • bio-molecular sensing
  • organic semiconductor laser
  • laser sensors


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