Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation

Helen C. Marshall; Samantha A. Campbell; Craig W. Roberts; Myra A. Nimmo

doi:10.1016/j.jtherbio.2007.04.003

Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation

Helen C. Marshall
, Samantha A. Campbell
, Craig W. Roberts
, Myra A. Nimmo

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

The timescale and integration of human whole body and cellular Hsp72 adaptations during the initial phase of human-heat acclimation were determined.

Two exercise humid-heat exposures on consecutive days lowered exercise rectal temperature (P < 0.05) and heart rate (P < 0.01).

Sweat rate was increased (P < 0.001) during exercise through an improved maintenance of sweating, and sweat Na+ reabsorption was enhanced (P < 0.05).

These adaptations were accompanied by a reduced Hsp72 mRNA response with no change in protein level.

Two prolonged, low-intensity exercise-heat bouts on consecutive days are sufficient to initiate physiological and Hsp72 mRNA adaptations, although Hsp72 protein adaptation may require a greater exercise intensity or longer acclimation period.

Original language	English
Pages (from-to)	341-348
Number of pages	8
Journal	Journal of Thermal Biology
Volume	32
Issue number	6
DOIs	https://doi.org/10.1016/j.jtherbio.2007.04.003
Publication status	Published - Aug 2007

Keywords

acclimation
heat shock protein 72
humid-heat stress
eccrine sweat gland
human-leukocytes
exercise
expression
responses
temperature
protein
plasma
HSP70
hot

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title = "Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation",

abstract = "The timescale and integration of human whole body and cellular Hsp72 adaptations during the initial phase of human-heat acclimation were determined. Two exercise humid-heat exposures on consecutive days lowered exercise rectal temperature (P < 0.05) and heart rate (P < 0.01). Sweat rate was increased (P < 0.001) during exercise through an improved maintenance of sweating, and sweat Na+ reabsorption was enhanced (P < 0.05). These adaptations were accompanied by a reduced Hsp72 mRNA response with no change in protein level. Two prolonged, low-intensity exercise-heat bouts on consecutive days are sufficient to initiate physiological and Hsp72 mRNA adaptations, although Hsp72 protein adaptation may require a greater exercise intensity or longer acclimation period.",

keywords = "acclimation, heat shock protein 72, humid-heat stress, eccrine sweat gland, human-leukocytes, exercise, expression, responses, temperature, protein, plasma, HSP70, hot",

author = "Marshall, \{Helen C.\} and Campbell, \{Samantha A.\} and Roberts, \{Craig W.\} and Nimmo, \{Myra A.\}",

year = "2007",

month = aug,

doi = "10.1016/j.jtherbio.2007.04.003",

language = "English",

volume = "32",

pages = "341--348",

journal = "Journal of Thermal Biology",

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publisher = "Elsevier Limited",

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TY - JOUR

T1 - Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation

AU - Marshall, Helen C.

AU - Campbell, Samantha A.

AU - Roberts, Craig W.

AU - Nimmo, Myra A.

PY - 2007/8

Y1 - 2007/8

N2 - The timescale and integration of human whole body and cellular Hsp72 adaptations during the initial phase of human-heat acclimation were determined. Two exercise humid-heat exposures on consecutive days lowered exercise rectal temperature (P < 0.05) and heart rate (P < 0.01). Sweat rate was increased (P < 0.001) during exercise through an improved maintenance of sweating, and sweat Na+ reabsorption was enhanced (P < 0.05). These adaptations were accompanied by a reduced Hsp72 mRNA response with no change in protein level. Two prolonged, low-intensity exercise-heat bouts on consecutive days are sufficient to initiate physiological and Hsp72 mRNA adaptations, although Hsp72 protein adaptation may require a greater exercise intensity or longer acclimation period.

AB - The timescale and integration of human whole body and cellular Hsp72 adaptations during the initial phase of human-heat acclimation were determined. Two exercise humid-heat exposures on consecutive days lowered exercise rectal temperature (P < 0.05) and heart rate (P < 0.01). Sweat rate was increased (P < 0.001) during exercise through an improved maintenance of sweating, and sweat Na+ reabsorption was enhanced (P < 0.05). These adaptations were accompanied by a reduced Hsp72 mRNA response with no change in protein level. Two prolonged, low-intensity exercise-heat bouts on consecutive days are sufficient to initiate physiological and Hsp72 mRNA adaptations, although Hsp72 protein adaptation may require a greater exercise intensity or longer acclimation period.

KW - acclimation

KW - heat shock protein 72

KW - humid-heat stress

KW - eccrine sweat gland

KW - human-leukocytes

KW - exercise

KW - expression

KW - responses

KW - temperature

KW - protein

KW - plasma

KW - HSP70

KW - hot

U2 - 10.1016/j.jtherbio.2007.04.003

DO - 10.1016/j.jtherbio.2007.04.003

M3 - Article

SN - 0306-4565

VL - 32

SP - 341

EP - 348

JO - Journal of Thermal Biology

JF - Journal of Thermal Biology

IS - 6

ER -

Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation

Abstract

Keywords

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