Human physiological and heat shock protein 72 adaptations during the initial phase of humid-heat acclimation

Helen C. Marshall, Samantha A. Campbell, Craig W. Roberts, Myra A. Nimmo

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The timescale and integration of human whole body and cellular Hsp72 adaptations during the initial phase of human-heat acclimation were determined.

Two exercise humid-heat exposures on consecutive days lowered exercise rectal temperature (P < 0.05) and heart rate (P < 0.01).

Sweat rate was increased (P < 0.001) during exercise through an improved maintenance of sweating, and sweat Na+ reabsorption was enhanced (P < 0.05).

These adaptations were accompanied by a reduced Hsp72 mRNA response with no change in protein level.

Two prolonged, low-intensity exercise-heat bouts on consecutive days are sufficient to initiate physiological and Hsp72 mRNA adaptations, although Hsp72 protein adaptation may require a greater exercise intensity or longer acclimation period.

Original languageEnglish
Pages (from-to)341-348
Number of pages8
JournalJournal of Thermal Biology
Volume32
Issue number6
DOIs
Publication statusPublished - Aug 2007

Keywords

  • acclimation
  • heat shock protein 72
  • humid-heat stress
  • eccrine sweat gland
  • human-leukocytes
  • exercise
  • expression
  • responses
  • temperature
  • protein
  • plasma
  • HSP70
  • hot

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