Human hepatic HepaRG cells maintain an organotypic phenotype with high intrinsic CYP450 activity/metabolism and significantly outperform standard HepG2/C3A cells for pharmaceutical and therapeutic applications

Leonard J. Nelson, Katie Morgan, Philipp Treskes, Kay Samuel, Catherine J. Henderson, Claire LeBled, Natalie Homer, M. Helen Grant, Peter C. Hayes, John N. Plevris