Hoechst 33258 and its complex with the oligonucleotide d(CGCGAATTCGCG)2: 1H NMR assignments and dynamics

John A. Parkinson; Jill Barber; Beverley A. Buckingham; Kenneth T. Douglas; Gareth A. Morris

doi:10.1002/mrc.1260301107

Hoechst 33258 and its complex with the oligonucleotide d(CGCGAATTCGCG)₂: 1H NMR assignments and dynamics

John A. Parkinson, Jill Barber, Beverley A. Buckingham, Kenneth T. Douglas, Gareth A. Morris

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

The ¹H NMR assignments of the 1:1 complex between d(CGCGAATTCGCG)₂ and the minor‐groove Hoechst 33258 ligand and the activation energy for the dissociation of the complex have been determined.

Original language	English
Pages (from-to)	1064-1069
Number of pages	6
Journal	Magnetic Resonance in Chemistry
Volume	30
Issue number	11
DOIs	https://doi.org/10.1002/mrc.1260301107
Publication status	Published - 1 Nov 1992

Keywords

d(CGCGAATTCGCG)2
oligonucleotide
ligand-DNA binding

Access to Document

10.1002/mrc.1260301107

Cite this

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title = "Hoechst 33258 and its complex with the oligonucleotide d(CGCGAATTCGCG)2: 1H NMR assignments and dynamics",

abstract = "The 1H NMR assignments of the 1:1 complex between d(CGCGAATTCGCG)2 and the minor‐groove Hoechst 33258 ligand and the activation energy for the dissociation of the complex have been determined.",

keywords = "d(CGCGAATTCGCG)2, oligonucleotide, ligand-DNA binding",

author = "Parkinson, {John A.} and Jill Barber and Buckingham, {Beverley A.} and Douglas, {Kenneth T.} and Morris, {Gareth A.}",

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T2 - 1H NMR assignments and dynamics

AU - Parkinson, John A.

AU - Barber, Jill

AU - Buckingham, Beverley A.

AU - Douglas, Kenneth T.

AU - Morris, Gareth A.

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AB - The 1H NMR assignments of the 1:1 complex between d(CGCGAATTCGCG)2 and the minor‐groove Hoechst 33258 ligand and the activation energy for the dissociation of the complex have been determined.

KW - d(CGCGAATTCGCG)2

KW - oligonucleotide

KW - ligand-DNA binding

U2 - 10.1002/mrc.1260301107

DO - 10.1002/mrc.1260301107

M3 - Article

SN - 0749-1581

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EP - 1069

JO - Magnetic Resonance in Chemistry

JF - Magnetic Resonance in Chemistry

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