HIP1 as a marker of aggressive prostate cancer

E Y W Chan

doi:10.1034/j.1399-0004.2002.620503_4.x

HIP1 as a marker of aggressive prostate cancer

E Y W Chan

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article

2 Citations (Scopus)

Abstract

A recent report from Theadora Ross’s group describes an exciting link between huntingtin interacting protein-1 (HIP1) and prostate cancer, providing further evidence for a critical role of this protein in the regulation of cell survival. HIP1 was initially identified by virtue of its interaction with huntingtin, the protein mutated in the neurodegenerative disorder Huntington disease (HD). The role of HIP1 in HD has been postulated to reflect a pro-apoptotic function in the cytoplasm (4,5).

Original language	English
Pages (from-to)	372-375
Number of pages	4
Journal	Clinical Genetics
Volume	62
Issue number	5
DOIs	https://doi.org/10.1034/j.1399-0004.2002.620503_4.x
Publication status	Published - Nov 2002

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

carrier proteins
DNA-binding proteins
humans
male
prostate-specific antigen
prostatic neoplasms
tumor markers, biological

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10.1034/j.1399-0004.2002.620503_4.x

Cite this

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title = "HIP1 as a marker of aggressive prostate cancer",

abstract = "A recent report from Theadora Ross{\textquoteright}s group describes an exciting link between huntingtin interacting protein-1 (HIP1) and prostate cancer, providing further evidence for a critical role of this protein in the regulation of cell survival. HIP1 was initially identified by virtue of its interaction with huntingtin, the protein mutated in the neurodegenerative disorder Huntington disease (HD). The role of HIP1 in HD has been postulated to reflect a pro-apoptotic function in the cytoplasm (4,5).",

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AB - A recent report from Theadora Ross’s group describes an exciting link between huntingtin interacting protein-1 (HIP1) and prostate cancer, providing further evidence for a critical role of this protein in the regulation of cell survival. HIP1 was initially identified by virtue of its interaction with huntingtin, the protein mutated in the neurodegenerative disorder Huntington disease (HD). The role of HIP1 in HD has been postulated to reflect a pro-apoptotic function in the cytoplasm (4,5).

KW - carrier proteins

KW - DNA-binding proteins

KW - humans

KW - male

KW - prostate-specific antigen

KW - prostatic neoplasms

KW - tumor markers, biological

U2 - 10.1034/j.1399-0004.2002.620503_4.x

DO - 10.1034/j.1399-0004.2002.620503_4.x

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JF - Clinical Genetics

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HIP1 as a marker of aggressive prostate cancer

Abstract

UN SDGs

Keywords

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