Highly efficient methods for the one-pot synthesis of b-substituted enones

W.J. Kerr, C.M. Pearson, G.J. Thurston

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

A mild and practically-convenient one-pot procedure for the direct b-substitution of enones has been developed using a conjugate addition–oxidation strategy with a full range of copper-based reagents and N-tert-butylphenylsulfinimidoyl
chloride; alkyl- and aryl-substituted enones are delivered in good to excellent yields.
LanguageEnglish
Pages47-50
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume4
Early online date25 Nov 2005
DOIs
Publication statusPublished - 2006

Fingerprint

reagents
Copper
Substitution reactions
substitutes
copper
Oxidation
oxidation
synthesis

Keywords

  • enones
  • chemistry
  • one pot synthesis

Cite this

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Highly efficient methods for the one-pot synthesis of b-substituted enones. / Kerr, W.J.; Pearson, C.M.; Thurston, G.J.

In: Organic and Biomolecular Chemistry, Vol. 4, 2006, p. 47-50.

Research output: Contribution to journalArticle

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AU - Thurston, G.J.

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AB - A mild and practically-convenient one-pot procedure for the direct b-substitution of enones has been developed using a conjugate addition–oxidation strategy with a full range of copper-based reagents and N-tert-butylphenylsulfinimidoylchloride; alkyl- and aryl-substituted enones are delivered in good to excellent yields.

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