Highly active iridium (I) complexes for catalytic hydrogen isotope exchange

J.A. Brown, S. Irvine, A.R. Kennedy, W.J. Kerr, S. Andersson, G.N. Nilsson

Research output: Contribution to journalArticle

82 Citations (Scopus)

Abstract

This poster, presented at the 16th annual symposium of the International Isotope Society's United Kingdom Group took place at the Wellcome Genome Campus, Hinxton, Cambridge, UK on 1st November 2007, reveals a series of novel iridium (I) complexes of type 2, and highlights their considerable efficiency and general applicability in the field of hydrogen isotope exchange, with levels as low as only 0.5 mol% catalyst loading over short reaction times being required to deliver extremely high levels of labelling.
Original languageEnglish
Pages (from-to)257-257
Number of pages1
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume51
Issue number5-6
DOIs
Publication statusPublished - Apr 2008

Keywords

  • hydrogen isotope exchange
  • potential drug candidate
  • metabolic pathway
  • iridium
  • catalyst
  • labelling

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