Highlights of natural compounds in prostate cancer drug discovery

Jorge A. R. Salvador, Vânia M. Moreira

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Abstract

The remarkable impact of natural products (NPs) in the quest for new agents and new directions in medicinal discovery is well established. The exploration of Nature as a source of novel active agents that may serve as leads and scaffolds for drugs targeting a myriad of diseases and the use of synthetic organic chemistry to modify them have been a driving force for drug discovery. Worldwide, prostate cancer (PC) is the second leading cause of death after lung cancer on both USA and Australia, and the third after lung and colo-rectal cancers in Europe.
Original languageEnglish
Title of host publicationProstate Cancer - From Bench to Bedside
EditorsPhilippe E. Spiess
Place of PublicationLondon
Pages463-492
Number of pages30
DOIs
Publication statusPublished - 25 Nov 2011

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Keywords

  • natural products
  • prostate cancer
  • cancer drugs
  • drug discovery

Cite this

Salvador, J. A. R., & Moreira, V. M. (2011). Highlights of natural compounds in prostate cancer drug discovery. In P. E. Spiess (Ed.), Prostate Cancer - From Bench to Bedside (pp. 463-492). London. https://doi.org/10.5772/27401