High throughput screening approach to lead discovery

Zoran Rankovic, Craig Jamieson, Richard. Morphy

Research output: Chapter in Book/Report/Conference proceedingOther chapter contribution

7 Citations (Scopus)

Abstract

A review. A review on high throughput screening (HTS) strategies for lead discovery. Topics covered include: historical background; screening collection enhancement strategies; HTS assays and equipment; hit confirmation and assessment; and successes, failures, and examples of HTS.
Original languageEnglish
Title of host publicationLead Generation Approaches in Drug Discovery
Place of PublicationHoboken, NJ
Pages21-71
Number of pages51
Publication statusPublished - 2010

Keywords

  • screening
  • high throughput screening
  • screening collection enhancement strategies

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