Abstract
Electrochemical transformations involve complex parameter interactions, ranging from universal chemistry variables such as solvent and reagents to specialist factors including electrode material and current density. Hence, the development of a robust and scale-independent electrochemical reaction can currently be a challenge. High-throughput experimentation (HTE) is an enabling method for reaction optimization and robustness testing. Here we provide an industrial and academic perspective on the state of the art of the combination of HTE with electrochemical reaction optimization for applications, including scale-up. We then present our vision for a future in which HTE reduces barriers to wide adoption of electrochemistry across the field of chemical synthesis.
| Original language | English |
|---|---|
| Pages (from-to) | 2587-2600 |
| Number of pages | 14 |
| Journal | Organic Process Research and Development |
| Volume | 25 |
| Issue number | 12 |
| Early online date | 3 Aug 2021 |
| DOIs | |
| Publication status | Published - 17 Dec 2021 |
Funding
Financial support for this work was provided by the CNRS, French Ministry of Research, and the University of Lyon I. A.G.W. thanks the GlaxoSmithKline/University of Strathclyde Collaborative Ph.D. program and the EPSRC for funding via Prosperity Partnership EP/S035990/1. S.C. thanks the ICBMS for a Master’s fellowship.
Keywords
- electrochemistry
- high-throughput
- technology acceptance
- method development
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