High-power laser production of PET isotopes

L. Robson, P. McKenna, T. McCanny, K.W.D. Ledingham, J.M. Gillies, J. Zweit

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

Recent experiments have demonstrated that laser-solid interactions at intensities greater than 1019 W/cm2 can produce fast electron beams of several hundred MeV [1], tens of MeV γ-rays [2, 3], up to 58MeV proton beams [4, 5], and heavier ions [6] of up to 7MeV/nucleon. One of the potential applications of the high-energy proton beams is the production of radioactive isotopes for positron emission tomography (PET). PET is a form of medical imaging requiring the production of short-lived positron emitting isotopes 11C, 13N, 15O, and 18F, by proton irradiation of natural/enriched targets using cyclotrons. PET development has been limited because of the size and shielding requirements of the nuclear installations. Recent results have shown when an intense laser beam interacts with solid targets, tens of MeV protons capable of producing PET isotopes are generated [7, 8, 9].

LanguageEnglish
Title of host publicationLasers and Nuclei
Subtitle of host publicationApplications of Ultrahigh Intensity Lasers in Nuclear Science
EditorsHeinrich Schwoerer, Burgard Beleites, Joseph Magill
Place of PublicationBerlin
PublisherSpringer
Pages191-203
Number of pages13
ISBN (Print)3540302719, 9783540302711
DOIs
Publication statusPublished - 22 May 2006

Publication series

NameLecture Notes in Physics
Volume694
ISSN (Print)0075-8450

Fingerprint

high power lasers
positrons
isotopes
tomography
proton beams
proton irradiation
radioactive isotopes
installing
cyclotrons
shielding
heavy ions
laser beams
gamma rays
electron beams
requirements
protons
lasers
interactions
energy

Keywords

  • positron emission tomography
  • laser irradiance
  • rutherford appleton laboratory
  • single laser shot
  • intense laser beam

Cite this

Robson, L., McKenna, P., McCanny, T., Ledingham, K. W. D., Gillies, J. M., & Zweit, J. (2006). High-power laser production of PET isotopes. In H. Schwoerer, B. Beleites, & J. Magill (Eds.), Lasers and Nuclei: Applications of Ultrahigh Intensity Lasers in Nuclear Science (pp. 191-203). (Lecture Notes in Physics; Vol. 694). Berlin: Springer. https://doi.org/10.1007/3-540-30272-7_12
Robson, L. ; McKenna, P. ; McCanny, T. ; Ledingham, K.W.D. ; Gillies, J.M. ; Zweit, J. / High-power laser production of PET isotopes. Lasers and Nuclei: Applications of Ultrahigh Intensity Lasers in Nuclear Science. editor / Heinrich Schwoerer ; Burgard Beleites ; Joseph Magill. Berlin : Springer, 2006. pp. 191-203 (Lecture Notes in Physics).
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Robson, L, McKenna, P, McCanny, T, Ledingham, KWD, Gillies, JM & Zweit, J 2006, High-power laser production of PET isotopes. in H Schwoerer, B Beleites & J Magill (eds), Lasers and Nuclei: Applications of Ultrahigh Intensity Lasers in Nuclear Science. Lecture Notes in Physics, vol. 694, Springer, Berlin, pp. 191-203. https://doi.org/10.1007/3-540-30272-7_12

High-power laser production of PET isotopes. / Robson, L.; McKenna, P.; McCanny, T.; Ledingham, K.W.D.; Gillies, J.M.; Zweit, J.

Lasers and Nuclei: Applications of Ultrahigh Intensity Lasers in Nuclear Science. ed. / Heinrich Schwoerer; Burgard Beleites; Joseph Magill. Berlin : Springer, 2006. p. 191-203 (Lecture Notes in Physics; Vol. 694).

Research output: Chapter in Book/Report/Conference proceedingChapter

TY - CHAP

T1 - High-power laser production of PET isotopes

AU - Robson, L.

AU - McKenna, P.

AU - McCanny, T.

AU - Ledingham, K.W.D.

AU - Gillies, J.M.

AU - Zweit, J.

PY - 2006/5/22

Y1 - 2006/5/22

N2 - Recent experiments have demonstrated that laser-solid interactions at intensities greater than 1019 W/cm2 can produce fast electron beams of several hundred MeV [1], tens of MeV γ-rays [2, 3], up to 58MeV proton beams [4, 5], and heavier ions [6] of up to 7MeV/nucleon. One of the potential applications of the high-energy proton beams is the production of radioactive isotopes for positron emission tomography (PET). PET is a form of medical imaging requiring the production of short-lived positron emitting isotopes 11C, 13N, 15O, and 18F, by proton irradiation of natural/enriched targets using cyclotrons. PET development has been limited because of the size and shielding requirements of the nuclear installations. Recent results have shown when an intense laser beam interacts with solid targets, tens of MeV protons capable of producing PET isotopes are generated [7, 8, 9].

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KW - positron emission tomography

KW - laser irradiance

KW - rutherford appleton laboratory

KW - single laser shot

KW - intense laser beam

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Robson L, McKenna P, McCanny T, Ledingham KWD, Gillies JM, Zweit J. High-power laser production of PET isotopes. In Schwoerer H, Beleites B, Magill J, editors, Lasers and Nuclei: Applications of Ultrahigh Intensity Lasers in Nuclear Science. Berlin: Springer. 2006. p. 191-203. (Lecture Notes in Physics). https://doi.org/10.1007/3-540-30272-7_12