TY - CHAP
T1 - High-power laser production of PET isotopes
AU - Robson, L.
AU - McKenna, P.
AU - McCanny, T.
AU - Ledingham, K.W.D.
AU - Gillies, J.M.
AU - Zweit, J.
PY - 2006/5/22
Y1 - 2006/5/22
N2 - Recent experiments have demonstrated that laser-solid interactions at intensities greater than 1019 W/cm2 can produce fast electron beams of several hundred MeV [1], tens of MeV γ-rays [2, 3], up to 58MeV proton beams [4, 5], and heavier ions [6] of up to 7MeV/nucleon. One of the potential applications of the high-energy proton beams is the production of radioactive isotopes for positron emission tomography (PET). PET is a form of medical imaging requiring the production of short-lived positron emitting isotopes 11C, 13N, 15O, and 18F, by proton irradiation of natural/enriched targets using cyclotrons. PET development has been limited because of the size and shielding requirements of the nuclear installations. Recent results have shown when an intense laser beam interacts with solid targets, tens of MeV protons capable of producing PET isotopes are generated [7, 8, 9].
AB - Recent experiments have demonstrated that laser-solid interactions at intensities greater than 1019 W/cm2 can produce fast electron beams of several hundred MeV [1], tens of MeV γ-rays [2, 3], up to 58MeV proton beams [4, 5], and heavier ions [6] of up to 7MeV/nucleon. One of the potential applications of the high-energy proton beams is the production of radioactive isotopes for positron emission tomography (PET). PET is a form of medical imaging requiring the production of short-lived positron emitting isotopes 11C, 13N, 15O, and 18F, by proton irradiation of natural/enriched targets using cyclotrons. PET development has been limited because of the size and shielding requirements of the nuclear installations. Recent results have shown when an intense laser beam interacts with solid targets, tens of MeV protons capable of producing PET isotopes are generated [7, 8, 9].
KW - positron emission tomography
KW - laser irradiance
KW - rutherford appleton laboratory
KW - single laser shot
KW - intense laser beam
UR - http://www.scopus.com/inward/record.url?scp=33749187645&partnerID=8YFLogxK
UR - https://link.springer.com/book/10.1007/b11559214
U2 - 10.1007/3-540-30272-7_12
DO - 10.1007/3-540-30272-7_12
M3 - Chapter
AN - SCOPUS:33749187645
SN - 3540302719
SN - 9783540302711
T3 - Lecture Notes in Physics
SP - 191
EP - 203
BT - Lasers and Nuclei
A2 - Schwoerer, Heinrich
A2 - Beleites, Burgard
A2 - Magill, Joseph
PB - Springer
CY - Berlin
ER -