1,1,1,2-Tetrafluoroethane (HFC-134a) has been transformed into a range of -fluoroenones via a direct route. Dehydrofluorination/metallation allowed trifluorovinylsilanes to be prepared; these could be converted in situ, or isolated and treated further, with alkyllithium reagents to give difluorovinylsilanes. Fluoride-catalysed addition to aldehydes followed by acidic work-up allowed the isolation of a range of -fluoroenones in two- or three-pots.
Bainbridge, J. M., Corr, S., Kanai, M., & Percy, J. (2000). HFC-134a as a fluorinated building block: short syntheses of α-fluoroenones. Tetrahedron Letters, 41(6), 971–974. https://doi.org/10.1016/S0040-4039(99)02184-X