Projects per year
Introduction Pulmonary artery stenting and valve replacement (PVR) are common interventions in an increasing population of adult patients with previously repaired congenital heart disease . Indications for intervention include assessing regional haemodynamics and effects on right ventricular volume and function . The criterion for intervention remains largely empirical and the optimal timing remains unknown. This work aims to investigate the altered haemodynamic environment of adults with congenital heart disease, pre- and post- operative PVR to establish a computational fluid dynamic (CFD) derived metric for determining the optimal requirement for PVR and stenting. In this initial work, we present CFD results in simplified geometries representing the proximal pulmonary artery and bifurcation. Methods Blood flow simulations were performed using an implementation of the finite volume method. The flow was assumed to be incompressible and governed by the Newtonian Navier-Stokes equations. Physiological vessel dimensions and boundary conditions were used in the models. Local velocities and wall shear stress values were evaluated numerically. Results and Discussion Blood flow in the pulmonary bifurcation is strongly dependent on the local geometrical characteristics and haemodynamic conditions. An increase in the flow separation is observed when the angle of the bifurcation increases. In addition, the geometry has a significant effect on the velocities and shear stresses developed on the vessel wall. Future work will involve anatomically-correct reconstructions from CT and MRI image data of adult congenital heart patients that have or are about to undergo pulmonary valve replacement. Numerical studies of these models will provide an insight into the underlying flow mechanisms of more complex 3D patient-specific geometries.
|Number of pages||1|
|Publication status||Published - 22 Jul 2018|
|Event||13th World Congress in Computational Mechanics - New York city, New York, United States|
Duration: 22 Jul 2018 → 27 Jul 2018
|Conference||13th World Congress in Computational Mechanics|
|Period||22/07/18 → 27/07/18|
- pulmonary valve replacement
- congenital heart disease
- haemodynamic analysis
- haemodynamic environment
1/10/17 → 30/09/20
Project: Research - Studentship
Blood flow simulations in the pulmonary bifurcation in relation to adult patients with repaired tetralogy of FallotBoumpouli, M., Danton, M. H. D., Gourlay, T. & Kazakidi, A., 30 Nov 2020, In: Medical Engineering and Physics . 85, p. 123-138 16 p.
Research output: Contribution to journal › Article › peer-review