Projects per year
Abstract
Two-photon luminescence (TPL) from gold nanorods shows considerable potential in biological imaging. We study the imaging of gold nanorods in Madin-Darby canine kidney (MDCK) cells using fluorescence lifetime imaging microscopy (FLIM). FLIM provides images with better contrast and sensitivity than intensity imaging. The characteristic fluorescence lifetime of gold nanorods is found to be less than 100 ps, which can be used to distinguish gold nanorods from other fluorescent labels and endogenous fluorophores in lifetime imaging.
| Original language | English |
|---|---|
| Article number | 20504 |
| Number of pages | 3 |
| Journal | Journal of Biomedical Optics |
| Volume | 15 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2 Apr 2010 |
Keywords
- two-photon luminescence
- madin-darby canine kidney cells
- fluorescence lifetime imaging microscopy
- gold nanorods
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Dive into the research topics of 'Gold nanorods for fluorescence lifetime imaging in biology'. Together they form a unique fingerprint.Projects
- 1 Finished
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NMS: EPSRC Science and Innovation Nanometrology for Molecular Science, Medicine and Manufacture
Birch, D. (Principal Investigator), Dawson, M. (Co-investigator), Faulds, K. (Co-investigator), Girkin, J. (Co-investigator), Graham, D. (Co-investigator), Martin, R. (Co-investigator), O'Donnell, K. (Co-investigator), Rolinski, O. (Co-investigator), Smith, W. (Co-investigator) & Wynne, K. (Co-investigator)
Scottish Funding Council SFC, EPSRC (Engineering and Physical Sciences Research Council)
1/08/08 → 31/01/12
Project: Research