Glycosylated foldamers to probe the carbohydrate−carbohydrate interaction

Graham L. Simpson, Andrew H Gordon, David M. Lindsay, Netnapa Promsawan, Matthew P. Crump, Keith Mulholland, Barry R. Hayter, Timothy Gallagher

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)


The synthesis of a triglycosylated helical foldamer based on a combination of cyclopentyl- and pyrrolidinyl-based amino acids is described. This structure is stable in water, maintaining as it does a series of carbohydrate units in proximity to one another, and represents the basis of a new approach to the study of carbohydrate−carbohydrate interactions.
Original languageEnglish
Pages (from-to)10638-10639
Number of pages2
JournalJournal of the American Chemical Society
Issue number33
Publication statusPublished - 1 Aug 2006


  • foldamers
  • peptdies and proteins
  • carbohydrates
  • monomers
  • scaffolds


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