Abstract
A bioactivity-guided fractionation of the chloroform extract of the seeds of Picralima nitida using glucose uptake in fully differentiated 3T3-L1 adipocytes afforded six indole alkaloids (akuammicine, 10-deoxyakuammine, akuammine, akuammidine, burnamine and picraline) and a mixture of four 5-hydroxy tryptamine amides. Akuammicine accounted for the increase in glucose uptake observed in the chloroform extract. (C) 2009 Phytochemical Society of Europe.
| Original language | English |
|---|---|
| Pages (from-to) | 53-55 |
| Number of pages | 3 |
| Journal | Phytochemistry Letters |
| Volume | 3 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 12 Mar 2010 |
Keywords
- glucose uptake
- stimulatory effect
- akuammicine
- picralima nitida
- apocynaceae
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Shittu, H., Gray, A., Furman, B., & Young, L. (2010). Glucose uptake stimulatory effect of akuammicine from picralima nitida (Apocynaceae). Phytochemistry Letters, 3(1), 53-55. https://doi.org/10.1016/j.phytol.2009.11.003