Genomic analyses confirm close relatedness between Rhodococcus defluvii and Rhodococcus equi (Rhodococcus hoagii)

Vartul Sangal, Amanda L. Jones, Michael Goodfellow, Paul A. Hoskisson, Peter Kämpfer, Iain C. Sutcliffe

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Rhodococcus defluvii strain Ca11(T) was isolated from a bioreactor involved in extensive phosphorus removal. We have sequenced the whole genome of this strain, and our comparative genomic and phylogenetic analyses confirm its close relatedness with Rhodococcus equi (Rhodococcus hoagii) strains, which share >80 % of the gene content. The R. equi virulence plasmid is absent though most of the chromosomal R. equi virulence-associated genes are present in R. defluvii Ca11(T). These data suggest that although R. defluvii is an environmental organism, it has the potential to colonize animal hosts.

LanguageEnglish
Pages113-116
Number of pages4
JournalArchives of Microbiology
Volume197
Issue number1
Early online date20 Nov 2014
DOIs
Publication statusPublished - 1 Jan 2015

Fingerprint

Rhodococcus equi
Rhodococcus
Genes
Virulence
Bioreactors
Phosphorus
Animals
Plasmids
Genome

Keywords

  • base sequence
  • genes, bacterial
  • genome, bacterial
  • genomics
  • molecular sequence data
  • phylogeny
  • plasmids
  • Rhodococcus
  • Rhodococcus equi
  • virulence

Cite this

Sangal, Vartul ; Jones, Amanda L. ; Goodfellow, Michael ; Hoskisson, Paul A. ; Kämpfer, Peter ; Sutcliffe, Iain C. / Genomic analyses confirm close relatedness between Rhodococcus defluvii and Rhodococcus equi (Rhodococcus hoagii). In: Archives of Microbiology. 2015 ; Vol. 197, No. 1. pp. 113-116.
@article{fd8d518f1d9f43ef9b6a87bf1754b193,
title = "Genomic analyses confirm close relatedness between Rhodococcus defluvii and Rhodococcus equi (Rhodococcus hoagii)",
abstract = "Rhodococcus defluvii strain Ca11(T) was isolated from a bioreactor involved in extensive phosphorus removal. We have sequenced the whole genome of this strain, and our comparative genomic and phylogenetic analyses confirm its close relatedness with Rhodococcus equi (Rhodococcus hoagii) strains, which share >80 {\%} of the gene content. The R. equi virulence plasmid is absent though most of the chromosomal R. equi virulence-associated genes are present in R. defluvii Ca11(T). These data suggest that although R. defluvii is an environmental organism, it has the potential to colonize animal hosts.",
keywords = "base sequence, genes, bacterial, genome, bacterial, genomics, molecular sequence data, phylogeny, plasmids, Rhodococcus, Rhodococcus equi, virulence",
author = "Vartul Sangal and Jones, {Amanda L.} and Michael Goodfellow and Hoskisson, {Paul A.} and Peter K{\"a}mpfer and Sutcliffe, {Iain C.}",
note = "The final publication is available at Springer via http://dx.doi.org/10.1007/s00203-014-1060-5",
year = "2015",
month = "1",
day = "1",
doi = "10.1007/s00203-014-1060-5",
language = "English",
volume = "197",
pages = "113--116",
journal = "Archives of Microbiology",
issn = "0302-8933",
number = "1",

}

Genomic analyses confirm close relatedness between Rhodococcus defluvii and Rhodococcus equi (Rhodococcus hoagii). / Sangal, Vartul; Jones, Amanda L.; Goodfellow, Michael; Hoskisson, Paul A.; Kämpfer, Peter; Sutcliffe, Iain C.

In: Archives of Microbiology, Vol. 197, No. 1, 01.01.2015, p. 113-116.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Genomic analyses confirm close relatedness between Rhodococcus defluvii and Rhodococcus equi (Rhodococcus hoagii)

AU - Sangal, Vartul

AU - Jones, Amanda L.

AU - Goodfellow, Michael

AU - Hoskisson, Paul A.

AU - Kämpfer, Peter

AU - Sutcliffe, Iain C.

N1 - The final publication is available at Springer via http://dx.doi.org/10.1007/s00203-014-1060-5

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Rhodococcus defluvii strain Ca11(T) was isolated from a bioreactor involved in extensive phosphorus removal. We have sequenced the whole genome of this strain, and our comparative genomic and phylogenetic analyses confirm its close relatedness with Rhodococcus equi (Rhodococcus hoagii) strains, which share >80 % of the gene content. The R. equi virulence plasmid is absent though most of the chromosomal R. equi virulence-associated genes are present in R. defluvii Ca11(T). These data suggest that although R. defluvii is an environmental organism, it has the potential to colonize animal hosts.

AB - Rhodococcus defluvii strain Ca11(T) was isolated from a bioreactor involved in extensive phosphorus removal. We have sequenced the whole genome of this strain, and our comparative genomic and phylogenetic analyses confirm its close relatedness with Rhodococcus equi (Rhodococcus hoagii) strains, which share >80 % of the gene content. The R. equi virulence plasmid is absent though most of the chromosomal R. equi virulence-associated genes are present in R. defluvii Ca11(T). These data suggest that although R. defluvii is an environmental organism, it has the potential to colonize animal hosts.

KW - base sequence

KW - genes, bacterial

KW - genome, bacterial

KW - genomics

KW - molecular sequence data

KW - phylogeny

KW - plasmids

KW - Rhodococcus

KW - Rhodococcus equi

KW - virulence

UR - http://link.springer.com/article/10.1007%2Fs00203-014-1060-5

U2 - 10.1007/s00203-014-1060-5

DO - 10.1007/s00203-014-1060-5

M3 - Article

VL - 197

SP - 113

EP - 116

JO - Archives of Microbiology

T2 - Archives of Microbiology

JF - Archives of Microbiology

SN - 0302-8933

IS - 1

ER -