Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

Rebecca E. McHugh; John T. Munnoch; Andrew J. Roe; Paul A. Hoskisson

doi:10.1099/acmi.0.000358

Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

Rebecca E. McHugh, John T. Munnoch, Andrew J. Roe, Paul A. Hoskisson

Strathclyde Institute Of Pharmacy And Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

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Abstract

We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71 %. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.

Original language	English
Article number	000358
Number of pages	5
Journal	Access Microbiology
Volume	4
Issue number	5
DOIs	https://doi.org/10.1099/acmi.0.000358
Publication status	Published - 30 May 2022

Keywords

Streptomyces goldiniensis ATCC 21386
genome sequence
multiplatform hybrid approach

Access to Document

10.1099/acmi.0.000358Licence: CC BY 4.0

McHugh-etal-AM-2022-Genome-sequence-of-the-aurodox-producing-bacteriumFinal published version, 544 KBLicence: CC BY 4.0

Chance and Necessity: Evolution guided antibiotic improvement and discovery
Hoskisson, P. (Principal Investigator)
BBSRC (Biotech & Biological Sciences Research Council)
1/10/19 → 30/09/22
Project: Research
Re-engineering robustness in to industrial antibiotic producing Streptomyces strains (Super Follow on Fund)
Hoskisson, P. (Principal Investigator) & Hunter, I. (Co-investigator)
BBSRC (Biotech & Biological Sciences Research Council)
1/10/19 → 31/08/22
Project: Research

Cite this

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title = "Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386",

abstract = "We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of \textasciitilde{}10 Mbp with a G+C content of 71 \%. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141. ",

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year = "2022",

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AU - Roe, Andrew J.

AU - Hoskisson, Paul A.

PY - 2022/5/30

Y1 - 2022/5/30

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AB - We report the genome sequence of Streptomyces goldiniensis ATCC 21386, a strain which produces the anti-bacterial and anti-virulence polyketide, aurodox. The genome of S. goldiniensis ATCC 21386 was sequenced using a multiplatform hybrid approach, revealing a linear genome of ~10 Mbp with a G+C content of 71 %. The genome sequence revealed 36 putative biosynthetic gene clusters (BGCs), including a large region of 271 Kbp that was rich in biosynthetic capability. The genome sequence is deposited in DDBJ/EMBL/GenBank with the accession number PRJNA602141.

KW - Streptomyces goldiniensis ATCC 21386

KW - genome sequence

KW - multiplatform hybrid approach

U2 - 10.1099/acmi.0.000358

DO - 10.1099/acmi.0.000358

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JO - Access Microbiology

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Genome sequence of the aurodox-producing bacterium Streptomyces goldiniensis ATCC 21386

Abstract

Keywords

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Projects

Chance and Necessity: Evolution guided antibiotic improvement and discovery

Re-engineering robustness in to industrial antibiotic producing Streptomyces strains (Super Follow on Fund)

Cite this