Genome editing reveals that pSCL4 is required for chromosome linearity in Streptomyces clavuligerus

Juan Pablo Gomez-Escribano, Lis Algora Gallardo, Kenan A. J. Bozhüyük, Steven G. Kendrew, Benjamin D. Huckle, Nicola A. Crowhurst, Mervyn J. Bibb, Andrew J. Collis, Jason Micklefield, Paul R. Herron, Barrie Wilkinson

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Biochemistry, Genetics and Molecular Biology