Abstract
Insulin resistance is linked to altered fat metabolism and elevated expression of inflammatory cytokines, particularly from fat tissue. This is turn is associated with obesity. It is proposed that NOD-like receptor expression may be responsible for inducing cytokine production from innate immune cells such as macrophages in fat tissue which in turn are linked to insulin resistance and obesity.
Original language | English |
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Pages | 501-502 |
Number of pages | 2 |
Volume | 23 |
No. | 5 |
Specialist publication | Current Opinion in Lipidology |
Publisher | Lippincott Williams and Wilkins |
DOIs | |
Publication status | Published - 1 Oct 2012 |
Keywords
- insulin resistance
- NOD-like receptors
- inflammatory cytokines
- macrophages
- obesity
- genetics
- molecular biology
- nucleotide oligomerization
- domain-like genes