Abstract
Maintaining stable cultures of viable and metabolically active primary hepatocytes is a long standing problem 1. Synthetic biomaterials with tuneable chemical properties may provide a suitable platform for the culture of primary cells. Hepatocytes are capable of binding terminal galactose residues via the hepatocyte asialoglycoprotein receptor (ASGPr); targeting of this receptor may facilitate binding of cells, influence morphology and ultimately improve cellular function 2
Original language | English |
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Pages (from-to) | 30 |
Number of pages | 1 |
Journal | European Cells and Materials |
Volume | 23 |
Issue number | Suppl 4 |
Publication status | Published - Jul 2012 |
Event | Tissue and Cell Engineering Society (TCES) meeting - Liverpool, United Kingdom Duration: 4 Jul 2012 → 6 Jul 2012 |
Keywords
- hepatocyte scaffold
- galactosylated poly(ethylene glycol)
- stable cultures