Galactosylated poly(ethylene glycol) as a scaffold for primary hepatocytes.

Research output: Contribution to journalMeeting abstract

Abstract

Maintaining stable cultures of viable and metabolically active primary hepatocytes is a long standing problem 1. Synthetic biomaterials with tuneable chemical properties may provide a suitable platform for the culture of primary cells. Hepatocytes are capable of binding terminal galactose residues via the hepatocyte asialoglycoprotein receptor (ASGPr); targeting of this receptor may facilitate binding of cells, influence morphology and ultimately improve cellular function 2
Original languageEnglish
Pages (from-to)30
Number of pages1
JournalEuropean Cells and Materials
Volume23
Issue numberSuppl 4
Publication statusPublished - Jul 2012
EventTissue and Cell Engineering Society (TCES) meeting - Liverpool, United Kingdom
Duration: 4 Jul 20126 Jul 2012

Keywords

  • hepatocyte scaffold
  • galactosylated poly(ethylene glycol)
  • stable cultures

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