Functional correlates of positional and gender-specific renal asymmetry in Drosophila

Venkateswara R Chintapalli, Selim Terhzaz, Jing Wang, Mohammed Al Bratty, David G Watson, Pawel Herzyk, Shireen A Davies, Julian A T Dow

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37 Citations (Scopus)
62 Downloads (Pure)


In humans and other animals, the internal organs are positioned asymmetrically in the body cavity, and disruption of this body plan can be fatal in humans. The mechanisms by which internal asymmetry are established are presently the subject of intense study; however, the functional significance of internal asymmetry (outside the brain) is largely unexplored. Is internal asymmetry functionally significant, or merely an expedient way of packing organs into a cavity?
Original languageEnglish
Pages (from-to)e32577
JournalPLOS One
Issue number4
Publication statusPublished - 4 Apr 2012


  • Drosophila
  • renal asymmetry
  • malpighian tubules
  • developmental genes
  • neuropeptide-F


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