Free recall of bound information held in short-term memory is unimpaired by age and education

Mônica Sanches Yassuda, Maria Teresa Carthery-Goulart, Mario Amore Cecchini, Luciana Cassimiro, Katarina Duarte Fernandes, Roberta Roque Baradel, Ricardo Basso Garcia, Ricardo Nitrini, Sergio Della Sala, Mario Parra Rodriguez

Research output: Contribution to journalReview article

Abstract

Objectives: It has been challenging to identify cognitive markers to differentiate healthy brain aging from neurodegeneration due to Alzheimer’s disease (AD) that are not affected by age and education. The Short-Term Memory Binding (STMB) showed not to be affected by age or education when using the change detection paradigm. However, no previous study has tested the effect of age and education using the free recall paradigm of the STMB. Therefore, the objective of this study was to investigate age and education effects on the free recall version of the STMB test under different memory loads. Methods: 126 healthy volunteers completed the free recall STMB test. The sample was divided into five age bands and into five education bands for comparisons. The STMB test assessed free recall of two (or three) common objects and two (or three) primary colors presented as individual features (unbound) or integrated into unified objects (bound). Results: The binding condition and the larger set size generated lower free recall scores. Performance was lower in older and less educated participants. Critically, neither age nor education modified these effects when compared across experimental conditions (unbound versus bound features). Conclusions: Binding in short-term memory carries a cost in performance. Age and education do not affect such a binding cost within a memory recall paradigm. These findings suggest that this paradigm is a suitable cognitive marker to differentiate healthy brain aging from age-related disease such as AD.
LanguageEnglish
JournalArchives of Clinical Neuropsychology
Publication statusAccepted/In press - 8 Mar 2019

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Short-Term Memory
Education
Alzheimer Disease
Costs and Cost Analysis
Brain
Healthy Volunteers
Color

Keywords

  • neuropsychology
  • learning and memory
  • working memory
  • short-term memory
  • cognitive aging
  • neurophyschological tests

Cite this

Yassuda, M. S., Carthery-Goulart, M. T., Cecchini, M. A., Cassimiro, L., Duarte Fernandes, K., Roque Baradel, R., ... Parra Rodriguez, M. (Accepted/In press). Free recall of bound information held in short-term memory is unimpaired by age and education. Archives of Clinical Neuropsychology.
Yassuda, Mônica Sanches ; Carthery-Goulart, Maria Teresa ; Cecchini, Mario Amore ; Cassimiro, Luciana ; Duarte Fernandes, Katarina ; Roque Baradel, Roberta ; Basso Garcia, Ricardo ; Nitrini, Ricardo ; Della Sala, Sergio ; Parra Rodriguez, Mario. / Free recall of bound information held in short-term memory is unimpaired by age and education. In: Archives of Clinical Neuropsychology. 2019.
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abstract = "Objectives: It has been challenging to identify cognitive markers to differentiate healthy brain aging from neurodegeneration due to Alzheimer’s disease (AD) that are not affected by age and education. The Short-Term Memory Binding (STMB) showed not to be affected by age or education when using the change detection paradigm. However, no previous study has tested the effect of age and education using the free recall paradigm of the STMB. Therefore, the objective of this study was to investigate age and education effects on the free recall version of the STMB test under different memory loads. Methods: 126 healthy volunteers completed the free recall STMB test. The sample was divided into five age bands and into five education bands for comparisons. The STMB test assessed free recall of two (or three) common objects and two (or three) primary colors presented as individual features (unbound) or integrated into unified objects (bound). Results: The binding condition and the larger set size generated lower free recall scores. Performance was lower in older and less educated participants. Critically, neither age nor education modified these effects when compared across experimental conditions (unbound versus bound features). Conclusions: Binding in short-term memory carries a cost in performance. Age and education do not affect such a binding cost within a memory recall paradigm. These findings suggest that this paradigm is a suitable cognitive marker to differentiate healthy brain aging from age-related disease such as AD.",
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Yassuda, MS, Carthery-Goulart, MT, Cecchini, MA, Cassimiro, L, Duarte Fernandes, K, Roque Baradel, R, Basso Garcia, R, Nitrini, R, Della Sala, S & Parra Rodriguez, M 2019, 'Free recall of bound information held in short-term memory is unimpaired by age and education' Archives of Clinical Neuropsychology.

Free recall of bound information held in short-term memory is unimpaired by age and education. / Yassuda, Mônica Sanches; Carthery-Goulart, Maria Teresa; Cecchini, Mario Amore; Cassimiro, Luciana ; Duarte Fernandes, Katarina ; Roque Baradel, Roberta ; Basso Garcia, Ricardo ; Nitrini, Ricardo; Della Sala, Sergio; Parra Rodriguez, Mario.

In: Archives of Clinical Neuropsychology, 08.03.2019.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Free recall of bound information held in short-term memory is unimpaired by age and education

AU - Yassuda, Mônica Sanches

AU - Carthery-Goulart, Maria Teresa

AU - Cecchini, Mario Amore

AU - Cassimiro, Luciana

AU - Duarte Fernandes, Katarina

AU - Roque Baradel, Roberta

AU - Basso Garcia, Ricardo

AU - Nitrini, Ricardo

AU - Della Sala, Sergio

AU - Parra Rodriguez, Mario

PY - 2019/3/8

Y1 - 2019/3/8

N2 - Objectives: It has been challenging to identify cognitive markers to differentiate healthy brain aging from neurodegeneration due to Alzheimer’s disease (AD) that are not affected by age and education. The Short-Term Memory Binding (STMB) showed not to be affected by age or education when using the change detection paradigm. However, no previous study has tested the effect of age and education using the free recall paradigm of the STMB. Therefore, the objective of this study was to investigate age and education effects on the free recall version of the STMB test under different memory loads. Methods: 126 healthy volunteers completed the free recall STMB test. The sample was divided into five age bands and into five education bands for comparisons. The STMB test assessed free recall of two (or three) common objects and two (or three) primary colors presented as individual features (unbound) or integrated into unified objects (bound). Results: The binding condition and the larger set size generated lower free recall scores. Performance was lower in older and less educated participants. Critically, neither age nor education modified these effects when compared across experimental conditions (unbound versus bound features). Conclusions: Binding in short-term memory carries a cost in performance. Age and education do not affect such a binding cost within a memory recall paradigm. These findings suggest that this paradigm is a suitable cognitive marker to differentiate healthy brain aging from age-related disease such as AD.

AB - Objectives: It has been challenging to identify cognitive markers to differentiate healthy brain aging from neurodegeneration due to Alzheimer’s disease (AD) that are not affected by age and education. The Short-Term Memory Binding (STMB) showed not to be affected by age or education when using the change detection paradigm. However, no previous study has tested the effect of age and education using the free recall paradigm of the STMB. Therefore, the objective of this study was to investigate age and education effects on the free recall version of the STMB test under different memory loads. Methods: 126 healthy volunteers completed the free recall STMB test. The sample was divided into five age bands and into five education bands for comparisons. The STMB test assessed free recall of two (or three) common objects and two (or three) primary colors presented as individual features (unbound) or integrated into unified objects (bound). Results: The binding condition and the larger set size generated lower free recall scores. Performance was lower in older and less educated participants. Critically, neither age nor education modified these effects when compared across experimental conditions (unbound versus bound features). Conclusions: Binding in short-term memory carries a cost in performance. Age and education do not affect such a binding cost within a memory recall paradigm. These findings suggest that this paradigm is a suitable cognitive marker to differentiate healthy brain aging from age-related disease such as AD.

KW - neuropsychology

KW - learning and memory

KW - working memory

KW - short-term memory

KW - cognitive aging

KW - neurophyschological tests

UR - https://academic.oup.com/acn

M3 - Review article

JO - Archives of Clinical Neuropsychology

T2 - Archives of Clinical Neuropsychology

JF - Archives of Clinical Neuropsychology

SN - 0887-6177

ER -

Yassuda MS, Carthery-Goulart MT, Cecchini MA, Cassimiro L, Duarte Fernandes K, Roque Baradel R et al. Free recall of bound information held in short-term memory is unimpaired by age and education. Archives of Clinical Neuropsychology. 2019 Mar 8.