Alkylation of the copper(II) chelates of acetylacetone and methyl acetoacetate by 3,3-dimethylallyl halides yields both 3,3-dimethylallyl and 1,1-dimethylallyl products. Formation of 1,1-dimethylallyl derivatives of these -polyketide analogues appears to be the results of a direct C-alkylation, and is a significant characteristic of the copper chelate reactions, which has not been observed previously with other alkylation reactions of -diketones or -keto-esters.
|Number of pages||3|
|Journal||Journal of the Chemical Society, Perkin Transactions 1|
|Publication status||Published - 1973|
- 3-dimethylallyl halides
- copper(ii) chelates
- methyl acetoacetate