Focused very high-energy electron beams as a novel radiotherapy modality for producing high-dose volumetric elements

K. Kokurewicz, E. Brunetti, G. H. Welsh, S. M. Wiggins, M. Boyd, A. Sorensen, A. J. Chalmers, G. Schettino, A. Subiel, C. DesRosiers, D. A. Jaroszynski

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Abstract

The increased inertia of very high-energy electrons (VHEEs) due to relativistic effects reduces scattering and enables irradiation of deep-seated tumours. However, entrance and exit doses are high for collimated or diverging beams. Here, we perform a study based on Monte Carlo simulations of focused VHEE beams in a water phantom, showing that dose can be concentrated into a small, well-defined volumetric element, which can be shaped or scanned to treat deep-seated tumours. The dose to surrounding tissue is distributed over a larger volume, which reduces peak surface and exit doses for a single beam by more than one order of magnitude compared with a collimated beam.
Original languageEnglish
Article number10837
Number of pages10
JournalScientific Reports
Volume9
DOIs
Publication statusPublished - 25 Jul 2019

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Keywords

  • very high-energy electrons (VHEEs)
  • relativistic effects
  • Monte Carlo simulations
  • deep-seated tumours
  • dose

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