Fmoc-diphenylalanine self assembles to a hydrogel via a novel architecture based on π–π interlocked β-sheets

Andrew Smith; Richard Williams; Claire Tang; Paolo Coppo; Richard Collins; Michael Turner; Alberto Saiani; Rein Vincent Ulijn

doi:10.1002/adma.200701221

Fmoc-diphenylalanine self assembles to a hydrogel via a novel architecture based on π–π interlocked β-sheets

Andrew Smith, Richard Williams, Claire Tang, Paolo Coppo, Richard Collins, Michael Turner, Alberto Saiani, Rein Vincent Ulijn

Pure And Applied Chemistry

Research output: Contribution to journal › Article › peer-review

905 Citations (Scopus)

Abstract

The self assembly of peptide hydrogelators that carry aromatic substituents can be modeled by a novel nanocylindrical architecture. The proposed model suggests that the nanocylinders are formed by anti-parallel β-sheets interlocked by the π-stacking interactions of fluorenyl groups and phenyl rings. This explanation is consistent with the structures observed in TEM and the data obtained by a variety of spectroscopic techniques.

Original language	English
Pages (from-to)	37-41
Number of pages	5
Journal	Advanced Materials
Volume	20
Issue number	1
Early online date	11 Dec 2007
DOIs	https://doi.org/10.1002/adma.200701221
Publication status	Published - 1 Jan 2008

Keywords

biomaterials
hydrogels
peptides

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10.1002/adma.200701221

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abstract = "The self assembly of peptide hydrogelators that carry aromatic substituents can be modeled by a novel nanocylindrical architecture. The proposed model suggests that the nanocylinders are formed by anti-parallel β-sheets interlocked by the π-stacking interactions of fluorenyl groups and phenyl rings. This explanation is consistent with the structures observed in TEM and the data obtained by a variety of spectroscopic techniques.",

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AU - Collins, Richard

AU - Turner, Michael

AU - Saiani, Alberto

AU - Ulijn, Rein Vincent

PY - 2008/1/1

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AB - The self assembly of peptide hydrogelators that carry aromatic substituents can be modeled by a novel nanocylindrical architecture. The proposed model suggests that the nanocylinders are formed by anti-parallel β-sheets interlocked by the π-stacking interactions of fluorenyl groups and phenyl rings. This explanation is consistent with the structures observed in TEM and the data obtained by a variety of spectroscopic techniques.

KW - biomaterials

KW - hydrogels

KW - peptides

U2 - 10.1002/adma.200701221

DO - 10.1002/adma.200701221

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JO - Advanced Materials

JF - Advanced Materials

IS - 1

ER -

Fmoc-diphenylalanine self assembles to a hydrogel via a novel architecture based on π–π interlocked β-sheets

Abstract

Keywords

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