Fluorinated succinic acid derivatives from new refrigerants via ozonolysis of haloalkenes

Samantha J Brown, Stuart Corr, Jonathan Percy

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Fluoro- and di-fluoro allylic alcohols obtained from HFC-134a and HCFC-133a were transformed through [3,3]-sigmatropic rearrangements into 3-fluoro-4-halo-4-alkenoates with variable substitution at the 2- and 3-positions. Ozonolysis of the haloalkenes afforded the corresponding acyl halides which could be trapped with nucleophiles to afford fluorinated succinic acid derivatives in which the two carboxylic acid groups were differentiated.
Original languageEnglish
Pages (from-to)5269-5273
Number of pages5
JournalTetrahedron Letters
Volume41
Issue number27
DOIs
Publication statusPublished - 1 Jul 2000

Keywords

  • allylic alcohols
  • ozonolysis
  • haloalkenes

Fingerprint Dive into the research topics of 'Fluorinated succinic acid derivatives from new refrigerants via ozonolysis of haloalkenes'. Together they form a unique fingerprint.

  • Cite this