Fluorescence lights the way to improving diabetes care

Research output: Contribution to conferenceSpeech

Abstract

The continuous monitoring of blood glucose levels for better management of diabetes is one of the grand challenges for sensing in the 21st century. Despite huge global investment this goal still remains elusive. In this talk I will review the fundamental issues surrounding the difficulty of in vivo glucose measurement and how spectroscopy and imagingare helping the research path to finding a workable sensor based on fluorescence. I will summarise some of the fluorescence methods tried so far, the potential advantages fluorescence lifetime measurements can bring, and describe promising sensors based on glucose/galactose binding protein labelled with environmentally sensitive fluorescent probes. I will include details of their design, characterization and specificity.
Original languageEnglish
Publication statusPublished - 14 Oct 2015
EventPHOTONEX - Technology and Innovation Centre, Glasgow, United Kingdom
Duration: 3 Jun 20153 Jun 2015

Conference

ConferencePHOTONEX
CountryUnited Kingdom
CityGlasgow
Period3/06/153/06/15

Fingerprint

glucose
luminaires
fluorescence
galactose
sensors
blood
proteins
life (durability)
probes
spectroscopy

Keywords

  • diabetes
  • fluorescence
  • glucose sensing

Cite this

Birch, D. (2015). Fluorescence lights the way to improving diabetes care. PHOTONEX , Glasgow, United Kingdom.
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Birch, D 2015, 'Fluorescence lights the way to improving diabetes care' PHOTONEX , Glasgow, United Kingdom, 3/06/15 - 3/06/15, .

Fluorescence lights the way to improving diabetes care. / Birch, David.

2015. PHOTONEX , Glasgow, United Kingdom.

Research output: Contribution to conferenceSpeech

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AB - The continuous monitoring of blood glucose levels for better management of diabetes is one of the grand challenges for sensing in the 21st century. Despite huge global investment this goal still remains elusive. In this talk I will review the fundamental issues surrounding the difficulty of in vivo glucose measurement and how spectroscopy and imagingare helping the research path to finding a workable sensor based on fluorescence. I will summarise some of the fluorescence methods tried so far, the potential advantages fluorescence lifetime measurements can bring, and describe promising sensors based on glucose/galactose binding protein labelled with environmentally sensitive fluorescent probes. I will include details of their design, characterization and specificity.

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Birch D. Fluorescence lights the way to improving diabetes care. 2015. PHOTONEX , Glasgow, United Kingdom.