Fluorescence guided surgery

Hazel L Stewart, David J S Birch

Research output: Contribution to journalReview articlepeer-review

33 Citations (Scopus)
14 Downloads (Pure)


Fluorescence guided surgery (FGS) is an imaging technique that allows the surgeon to visualise different structures and types of tissue during a surgical procedure that may not be as visible under white light conditions. Due to the many potential advantages of fluorescence guided surgery compared to more traditional clinical imaging techniques such as its higher contrast and sensitivity, less subjective use, and ease of instrument operation, the research interest in fluorescence guided surgery continues to grow over various key aspects such as fluorescent probe development and surgical system development as well as its potential clinical applications. This review looks to summarise some of the emerging opportunities and developments that have already been made in fluorescence guided surgery in recent years while highlighting its advantages as well as limitations that need to be overcome in order to utilise the full potential of fluorescence within the surgical environment.
Original languageEnglish
Article number042002
Number of pages26
JournalMethods and Applications in Fluorescence
Issue number4
Publication statusPublished - 26 Aug 2021


  • fluorescence guided surgery
  • FLIM
  • fluorescence lifetime
  • fluorescence probes
  • SPAD arrays
  • fluorescence imaging
  • intraoperative surgery


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