TY - JOUR
T1 - Fluid flow and mass transfer modelling in lysozyme ultrafiltration
AU - Magueijo, Vítor
AU - Semião, Viriato
AU - De Pinho, Maria Norberta
PY - 2005/4/1
Y1 - 2005/4/1
N2 - This work addresses the mass transfer modelling of ternary solutions, water/lysozyme/sodium chloride, in the slit feed channel of a ultrafiltration (UF) cell. Permeation experiments are performed using a laboratory-made UF cellulose acetate membrane, characterised by an hydraulic permeability of 2.05 × 10-11 m/s/Pa and a molecular weight cut-off of 30 kDa. The simulation of the UF operating conditions with recourse to computer fluid dynamics allows the prediction of the selective permeation performance in terms of permeation fluxes and concentration polarization. The predictions of the permeation fluxes based on different mass transport assumptions are compared with experimental ones and a good agreement is obtained.
AB - This work addresses the mass transfer modelling of ternary solutions, water/lysozyme/sodium chloride, in the slit feed channel of a ultrafiltration (UF) cell. Permeation experiments are performed using a laboratory-made UF cellulose acetate membrane, characterised by an hydraulic permeability of 2.05 × 10-11 m/s/Pa and a molecular weight cut-off of 30 kDa. The simulation of the UF operating conditions with recourse to computer fluid dynamics allows the prediction of the selective permeation performance in terms of permeation fluxes and concentration polarization. The predictions of the permeation fluxes based on different mass transport assumptions are compared with experimental ones and a good agreement is obtained.
KW - concentration polarization
KW - cross diffusion
KW - modelling
KW - protein
KW - ultrafiltration
UR - http://www.scopus.com/inward/record.url?scp=17644394182&partnerID=8YFLogxK
U2 - 10.1016/j.ijheatmasstransfer.2004.11.009
DO - 10.1016/j.ijheatmasstransfer.2004.11.009
M3 - Article
AN - SCOPUS:17644394182
SN - 0017-9310
VL - 48
SP - 1716
EP - 1726
JO - International Journal of Heat and Mass Transfer
JF - International Journal of Heat and Mass Transfer
IS - 9
ER -