Projects per year
Abstract
In recent years, cell therapy has emerged as a promising therapeutic strategy for many diseases, including Parkinson’s disease [1]. To increase cell viability, biomaterials are often used as scaffolds to facilitate cell deposition, through injection, to the site of interest. However, fluid forces acting on the cells during injection may lead to cell disruption or death [2]. This study aims to develop a novel device for the delivery of a cell-embedded collagen hydrogel, forming in situ. Here, we discuss computational results on constricted channels representing the connection between the syringe barrel and the needle to gain insight into the effect of syringe geometry.
Original language | English |
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Title of host publication | BioMedEng18 Proceedings |
Subtitle of host publication | The UK's largest gathering of Biomedical Engineers, Medical Engineers and Bioengineers |
Place of Publication | London |
Publication status | Published - 7 Sept 2018 |
Event | BioMedEng18 - Imperial College, London, United Kingdom Duration: 6 Sept 2018 → 7 Sept 2018 https://www.biomedeng18.com/ |
Conference
Conference | BioMedEng18 |
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Abbreviated title | BioMedEng |
Country/Territory | United Kingdom |
City | London |
Period | 6/09/18 → 7/09/18 |
Internet address |
Keywords
- cell therapy
- collagen gel
- syringe geometry
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Dive into the research topics of 'Flow simulation of a collagen solution in syringes with different geometries'. Together they form a unique fingerprint.Projects
- 2 Finished
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Multi-scale computational hemodynamics in obese children and adolescents: enabling personalised prediction of cardiovascular disease (CALLIRHEO) H2020 MSCA IF
Gourlay, T. (Co-investigator) & Kazakidi, A. (Fellow)
European Commission - Horizon Europe + H2020
1/01/18 → 31/12/19
Project: Research Fellowship
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Design and Development of a Delivery Device for an Injectable Collagen Scaffold by Computational and Experimental Analysis (ESR-15) for BrainMatTrain H2020 MSCA ITN ETN (676408)
Kazakidi, A. (Principal Investigator)
1/09/17 → 31/08/20
Project: Research - Studentship