Flow of a blood analogue solution through microfabricated hyperbolic contractions

P.C. Sousa, I.S. Pinho, F.T. Pinho, Monica Oliveira, M.A. Alves

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

6 Citations (Scopus)
90 Downloads (Pure)

Abstract

The flow of a blood analogue solution past a microfabricated hyperbolic
contraction followed by an abrupt expansion was investigated experimentally. The shape of the contraction was designed in order to impose a nearly constant strain rate to the fluid along the centerline of the microgeometry. The flow patterns of the blood analogue solution and of a Newtonian reference fluid (deionized water), captured using streak line imaging, are quite distinct and illustrate the complex behavior of the blood analogue solution flowing through the microgeometry. The flow of the blood analogue solution shows elastic-driven effects with vortical structures emerging upstream of the contraction, which are absent in Newtonian fluid flow. In both cases the flow also develops instabilities downstream of the expansion but these are inertia driven. Therefore, for the blood analogue solution at high flow rates the competing effects of inertia and elasticity lead to complex flow patterns and unstable flow develops.
Original languageEnglish
Title of host publicationComputational Vision and Medical Image Processing
Subtitle of host publicationRecent Trends
EditorsJ.M.R.S. Tavares, R.M.N. Jorge
Place of PublicationLondon
PublisherSpringer London
PagesCh 15 pp 265-279
Number of pages15
Volume19
Edition1st
ISBN (Print)978-94-007-0010-9
DOIs
Publication statusPublished - 2011

Publication series

NameComputational Methods in Applied Sciences
PublisherSpringer
Volume15

Keywords

  • blood analogue fluid
  • extensional flow
  • microfluidics
  • viscoelasticity
  • flow visualization
  • hyperbolic contraction

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