Flow of a blood analogue solution through microfabricated hyperbolic contractions

P.C. Sousa, I.S. Pinho, F.T. Pinho, Monica Oliveira, M.A. Alves

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

2 Citations (Scopus)

Abstract

The flow of a blood analogue solution past a microfabricated hyperbolic
contraction followed by an abrupt expansion was investigated experimentally. The shape of the contraction was designed in order to impose a nearly constant strain rate to the fluid along the centerline of the microgeometry. The flow patterns of the blood analogue solution and of a Newtonian reference fluid (deionized water), captured using streak line imaging, are quite distinct and illustrate the complex behavior of the blood analogue solution flowing through the microgeometry. The flow of the blood analogue solution shows elastic-driven effects with vortical structures emerging upstream of the contraction, which are absent in Newtonian fluid flow. In both cases the flow also develops instabilities downstream of the expansion but these are inertia driven. Therefore, for the blood analogue solution at high flow rates the competing effects of inertia and elasticity lead to complex flow patterns and unstable flow develops.
LanguageEnglish
Title of host publicationComputational Vision and Medical Image Processing
Subtitle of host publicationRecent Trends
EditorsJ.M.R.S. Tavares, R.M.N. Jorge
Place of PublicationLondon
PagesCh 15 pp 265-279
Number of pages15
Volume19
Edition1st
DOIs
Publication statusPublished - 2011

Publication series

NameComputational Methods in Applied Sciences
PublisherSpringer
Volume15

Fingerprint

Blood
Flow patterns
Fluids
Deionized water
Flow of fluids
Strain rate
Elasticity
Flow rate
Imaging techniques

Keywords

  • blood analogue fluid
  • extensional flow
  • microfluidics
  • viscoelasticity
  • flow visualization
  • hyperbolic contraction

Cite this

Sousa, P. C., Pinho, I. S., Pinho, F. T., Oliveira, M., & Alves, M. A. (2011). Flow of a blood analogue solution through microfabricated hyperbolic contractions. In J. M. R. S. Tavares, & R. M. N. Jorge (Eds.), Computational Vision and Medical Image Processing: Recent Trends (1st ed., Vol. 19, pp. Ch 15 pp 265-279). (Computational Methods in Applied Sciences; Vol. 15). London. https://doi.org/10.1007/978-94-007-0011-615
Sousa, P.C. ; Pinho, I.S. ; Pinho, F.T. ; Oliveira, Monica ; Alves, M.A. / Flow of a blood analogue solution through microfabricated hyperbolic contractions. Computational Vision and Medical Image Processing: Recent Trends. editor / J.M.R.S. Tavares ; R.M.N. Jorge. Vol. 19 1st . ed. London, 2011. pp. Ch 15 pp 265-279 (Computational Methods in Applied Sciences).
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Sousa, PC, Pinho, IS, Pinho, FT, Oliveira, M & Alves, MA 2011, Flow of a blood analogue solution through microfabricated hyperbolic contractions. in JMRS Tavares & RMN Jorge (eds), Computational Vision and Medical Image Processing: Recent Trends. 1st edn, vol. 19, Computational Methods in Applied Sciences, vol. 15, London, pp. Ch 15 pp 265-279. https://doi.org/10.1007/978-94-007-0011-615

Flow of a blood analogue solution through microfabricated hyperbolic contractions. / Sousa, P.C.; Pinho, I.S.; Pinho, F.T.; Oliveira, Monica; Alves, M.A.

Computational Vision and Medical Image Processing: Recent Trends. ed. / J.M.R.S. Tavares; R.M.N. Jorge. Vol. 19 1st . ed. London, 2011. p. Ch 15 pp 265-279 (Computational Methods in Applied Sciences; Vol. 15).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

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Sousa PC, Pinho IS, Pinho FT, Oliveira M, Alves MA. Flow of a blood analogue solution through microfabricated hyperbolic contractions. In Tavares JMRS, Jorge RMN, editors, Computational Vision and Medical Image Processing: Recent Trends. 1st ed. Vol. 19. London. 2011. p. Ch 15 pp 265-279. (Computational Methods in Applied Sciences). https://doi.org/10.1007/978-94-007-0011-615