Flexible access to conformationally-locked bicyclic morpholines

Rachael Bogacki; Duncan M. Gill; W. J. Kerr; Scott Lamont; John A. Parkinson; Laura C. Paterson

doi:10.1039/C3CC45627G

Flexible access to conformationally-locked bicyclic morpholines

Rachael Bogacki, Duncan M. Gill, W. J. Kerr, Scott Lamont, John A. Parkinson, Laura C. Paterson

Pure And Applied Chemistry

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Abstract

A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.

Original language	English
Pages (from-to)	8931-8933
Number of pages	3
Journal	Journal of the Chemical Society, Chemical Communications
Volume	49
Issue number	79
Early online date	15 Aug 2013
DOIs	https://doi.org/10.1039/C3CC45627G
Publication status	Published - 10 Sept 2013

Keywords

flexible access
conformationally-locked
bicyclic morpholines

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10.1039/C3CC45627G

Kerr-etal-CC2013-conformationally-locked-bicyclic-morpholinesAccepted author manuscript, 720 KB

Cite this

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title = "Flexible access to conformationally-locked bicyclic morpholines",

abstract = "A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.",

keywords = "flexible access, conformationally-locked, bicyclic morpholines",

author = "Rachael Bogacki and Gill, {Duncan M.} and Kerr, {W. J.} and Scott Lamont and Parkinson, {John A.} and Paterson, {Laura C.}",

year = "2013",

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T1 - Flexible access to conformationally-locked bicyclic morpholines

AU - Bogacki, Rachael

AU - Gill, Duncan M.

AU - Kerr, W. J.

AU - Lamont, Scott

AU - Parkinson, John A.

AU - Paterson, Laura C.

PY - 2013/9/10

Y1 - 2013/9/10

N2 - A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.

AB - A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.

KW - flexible access

KW - conformationally-locked

KW - bicyclic morpholines

UR - http://pubs.rsc.org/en/journals/journalissues/cc

U2 - 10.1039/C3CC45627G

DO - 10.1039/C3CC45627G

M3 - Article

SN - 0022-4936

VL - 49

SP - 8931

EP - 8933

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 79

ER -

Flexible access to conformationally-locked bicyclic morpholines

Abstract

Keywords

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