Flexible access to conformationally-locked bicyclic morpholines

Rachael Bogacki, Duncan M. Gill, W. J. Kerr, Scott Lamont, John A. Parkinson, Laura C. Paterson

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A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.
Original languageEnglish
Pages (from-to)8931-8933
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number79
Early online date15 Aug 2013
Publication statusPublished - 10 Sep 2013



  • flexible access
  • conformationally-locked
  • bicyclic morpholines

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