Introduction: This study aims to investigate in-hоsрitаl mоrtаlity in severe асute resрirаtоry syndrоme соrоnаvirus 2 раtients strаtified by serum ferritin levels. Methods: Patients were stratified based on ferritin levels (ferritin levels ≤ 1000 or >1000). Results: Approximately 89% (118) of the patients with ferritin levels > 1000 had pneumonia, and 51% (67) had hypertension. Fever (97, 73.5%) and shortness of breath (80, 61%) were two major symptoms among the patients in this group. Logistic regression analysis indicated that ferritin level (odds ratio [OR] = 0.36, 95% confidence interval [CI] = 0.21–0.62; p <.001), male sex (OR = 2.63, 95% CI = 1.43–5.06; p =.003), hypertension (OR = 4.16, 95% CI = 2.42–7.36; p <.001) and pneumonia (OR = 8.48, 95% CI = 3.02–35.45; p <.001) had significance in predicting in-hospital mortality. Additionally, the Cox proportional hazards analysis and Kaplan–Meier survival probability plot showed a higher mortality rate among patients with ferritin levels > 1000. Conclusion: In this study, higher levels of serum ferritin were found to be an independent predictor of in-hоsрitаl mоrtаlity.
|Number of pages||8|
|Journal||Immunity, Inflammation and Disease|
|Early online date||26 Aug 2021|
|Publication status||E-pub ahead of print - 26 Aug 2021|
- in-hospital mortality
- male sex