We report herein on the synthesis of some isatin Schiff’s bases (1–11), which were prepared from the reaction of isatin and some aromatic amines. These in turn were converted to the corresponding Mannich bases (12-23) by reaction with a number of secondary amines and formaldehyde, taking advantage of the active –NH group in the isatin. The structures of these compounds were elucidated using standard spectroscopic and analytical methods.
|Number of pages||12|
|Journal||Journal of Chemical, Biological and Physical Sciences|
|Publication status||Published - May 2015|
- Isatin Schiff’s
- Mannich bases
Al-kadhimi, A. A. H., Al-azzawi, N. K. E., & Khalaf, A. I. (2015). Facile synthesis of Schiff and Mannich bases of isatin derivatives. Journal of Chemical, Biological and Physical Sciences, 5(3), 2338-2349.