Fab I and inhibition of apicomplexan parasites

Rima McLeod (Inventor), Stephen Muench (Inventor), John Rafferty (Inventor), Dennis Kyle (Inventor), Ernest Mui (Inventor), Michael Kirisits (Inventor), Douglas Mack (Inventor), Craig Roberts (Inventor), Benjamin Samuel (Inventor), Russell Lyons (Inventor), Wilbur Milhous (Inventor), Sean Prigge (Inventor), David W. Rice (Inventor)

Research output: Patent

Abstract

Discovery and characterization of an apicomplexan Fab I gene and encoded enzyme and discovery of the triclosan as a lead compound, provide means to rationally design novel inhibitory compositions useful for prevention and treatment of apicomplexan related diseases.
LanguageEnglish
Patent numberUS 20040137446 A1
Priority date21/12/00
Publication statusPublished - 15 Jul 2004

Fingerprint

Triclosan
Parasites
Enzymes
Genes
Lead

Keywords

  • enzyme
  • inhibitor
  • apicomplexan infections

Cite this

McLeod, R., Muench, S., Rafferty, J., Kyle, D., Mui, E., Kirisits, M., ... Rice, D. W. (2004). Fab I and inhibition of apicomplexan parasites. (Patent No. US 20040137446 A1).
McLeod, Rima (Inventor) ; Muench, Stephen (Inventor) ; Rafferty, John (Inventor) ; Kyle, Dennis (Inventor) ; Mui, Ernest (Inventor) ; Kirisits, Michael (Inventor) ; Mack, Douglas (Inventor) ; Roberts, Craig (Inventor) ; Samuel, Benjamin (Inventor) ; Lyons, Russell (Inventor) ; Milhous, Wilbur (Inventor) ; Prigge, Sean (Inventor) ; Rice, David W. (Inventor). / Fab I and inhibition of apicomplexan parasites. Patent No.: US 20040137446 A1.
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title = "Fab I and inhibition of apicomplexan parasites",
abstract = "Discovery and characterization of an apicomplexan Fab I gene and encoded enzyme and discovery of the triclosan as a lead compound, provide means to rationally design novel inhibitory compositions useful for prevention and treatment of apicomplexan related diseases.",
keywords = "enzyme, inhibitor, apicomplexan infections",
author = "Rima McLeod and Stephen Muench and John Rafferty and Dennis Kyle and Ernest Mui and Michael Kirisits and Douglas Mack and Craig Roberts and Benjamin Samuel and Russell Lyons and Wilbur Milhous and Sean Prigge and Rice, {David W.}",
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McLeod, R, Muench, S, Rafferty, J, Kyle, D, Mui, E, Kirisits, M, Mack, D, Roberts, C, Samuel, B, Lyons, R, Milhous, W, Prigge, S & Rice, DW 2004, Fab I and inhibition of apicomplexan parasites, Patent No. US 20040137446 A1.

Fab I and inhibition of apicomplexan parasites. / McLeod, Rima (Inventor); Muench, Stephen (Inventor); Rafferty, John (Inventor); Kyle, Dennis (Inventor); Mui, Ernest (Inventor); Kirisits, Michael (Inventor); Mack, Douglas (Inventor); Roberts, Craig (Inventor); Samuel, Benjamin (Inventor); Lyons, Russell (Inventor); Milhous, Wilbur (Inventor); Prigge, Sean (Inventor); Rice, David W. (Inventor).

Patent No.: US 20040137446 A1.

Research output: Patent

TY - PAT

T1 - Fab I and inhibition of apicomplexan parasites

AU - McLeod, Rima

AU - Muench, Stephen

AU - Rafferty, John

AU - Kyle, Dennis

AU - Mui, Ernest

AU - Kirisits, Michael

AU - Mack, Douglas

AU - Roberts, Craig

AU - Samuel, Benjamin

AU - Lyons, Russell

AU - Milhous, Wilbur

AU - Prigge, Sean

AU - Rice, David W.

PY - 2004/7/15

Y1 - 2004/7/15

N2 - Discovery and characterization of an apicomplexan Fab I gene and encoded enzyme and discovery of the triclosan as a lead compound, provide means to rationally design novel inhibitory compositions useful for prevention and treatment of apicomplexan related diseases.

AB - Discovery and characterization of an apicomplexan Fab I gene and encoded enzyme and discovery of the triclosan as a lead compound, provide means to rationally design novel inhibitory compositions useful for prevention and treatment of apicomplexan related diseases.

KW - enzyme

KW - inhibitor

KW - apicomplexan infections

M3 - Patent

M1 - US 20040137446 A1

ER -

McLeod R, Muench S, Rafferty J, Kyle D, Mui E, Kirisits M et al, inventors. Fab I and inhibition of apicomplexan parasites. US 20040137446 A1. 2004 Jul 15.