Fab I and inhibition of apicomplexan parasites

Rima McLeod (Inventor), Stephen Muench (Inventor), John Rafferty (Inventor), Dennis Kyle (Inventor), Ernest Mui (Inventor), Michael Kirisits (Inventor), Douglas Mack (Inventor), Craig Roberts (Inventor), Benjamin Samuel (Inventor), Russell Lyons (Inventor), Wilbur Milhous (Inventor), Sean Prigge (Inventor), David W. Rice (Inventor)

Research output: Patent


Discovery and characterization of an apicomplexan Fab I gene and encoded enzyme and discovery of the triclosan as a lead compound, provide means to rationally design novel inhibitory compositions useful for prevention and treatment of apicomplexan related diseases.
Original languageEnglish
Patent numberUS 20040137446 A1
Priority date21/12/00
Publication statusPublished - 15 Jul 2004


  • enzyme
  • inhibitor
  • apicomplexan infections


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