Projects per year
Variables within sample collection, storage and preparation are explored in order to evaluate their effects on the spectral outcome, including; differences between sample collection tubes, centrifugal speed and time, short and long-term storage conditions, individual analyst technique, sample volumes, environment of sample batches, as well as various drying techniques. Exploratory data analysis using principal component analysis was implemented to unearth spectral variance not immediately observable.
Minor spectral variations were observed within each experiment; however, these were not considered significant differences as a result of these varying experimental factors. Variation between different operator techniques when preparing samples was observed, yet can be resolved with appropriate standard operating procedures, regardless of other factors such as sample volume and storage conditions. The findings within this report suggest that experimental variations within a laboratory, or between different laboratories, does not significantly affect the spectral outcome, and with good laboratory practice and careful sample handling results should be consistent and reliable.
- clinical spectroscopy
- pre-analytical variation
FingerprintDive into the research topics of 'Exploring pre-analytical factors for the optimisation of serum diagnostics: progressing the clinical utility of ATR-FTIR spectroscopy'. Together they form a unique fingerprint.
- 1 Finished
1/10/13 → 30/09/17
Project: Research - Studentship