Exploiting dimerization of purely peptidic amphiphiles to form vesicles

Thomas B. Schuster, Dirk De Bruyn Ouboter, Nico Bruns, Wolfgang Meier

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Short, amphiphilic peptides self-assemble into vesicles due to dimerization. These additional interactions lead to the formation of stable peptide membranes. The vesicles demonstrate pH responsiveness and the ability to encapsulate hydrophobic and hydrophilic moieties within their structure, and therefore may be used as an advanced, biodegradable, drug-delivery system.

Original languageEnglish
Pages (from-to)2158-2162
Number of pages5
JournalSmall
Volume7
Issue number15
DOIs
Publication statusPublished - 8 Aug 2011

Keywords

  • biomaterials
  • colloids
  • drug delivery
  • membranes
  • self-assembly

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