Evidence of VX nerve agent use from contaminated white mustard plants

Matthew R. Gravett, Farrha B. Hopkins, Adam J. Self, Andrew J. Webb, Christopher M. Timperley, Matthew J. Baker

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The Chemical Weapons Convention prohibits the development, production, acquisition, stockpiling, retention, transfer or use of chemical weapons by Member States. Verification of compliance and investigations into allegations of use require accurate detection of chemical warfare agents (CWAs) and their degradation products. Detection of CWAs such as organophosphorus nerve agents in the environment reliesmainly upon the analysis of soil.We now present a method for the detection of the nerve agent VX and its hydrolysis products by gas chromatography and liquid chromatography mass spectrometry of ethanol extracts of contaminated white mustard plants (Sinapis alba) which retained the compounds of interest for up to 45 days. VX is hydrolysed by the plants to ethyl methylphosphonic acid and then to methylphosphonic acid. The utility of white mustard as a nerve agent detector and remediator of nerve agent-polluted sites is discussed. The work described will help deter the employment of VX in conflict.

LanguageEnglish
Article number20140076
Number of pages14
JournalProceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences
Volume470
Issue number2168
DOIs
Publication statusPublished - 8 Aug 2014

Fingerprint

nerves
Nerve
chemical warfare
Chemical warfare
weapons
stockpiling
Gas Chromatography
acids
Acids
Liquid chromatography
liquid chromatography
Ethanol
Mass Spectrometry
chromatography
products
gas chromatography
Chromatography
Compliance
Gas chromatography
Mass spectrometry

Keywords

  • chemical weapons
  • gas chromatography
  • liquid chromatography
  • mass spectrometry
  • Sinapis alba
  • VX
  • white mustard

Cite this

Gravett, Matthew R. ; Hopkins, Farrha B. ; Self, Adam J. ; Webb, Andrew J. ; Timperley, Christopher M. ; Baker, Matthew J. / Evidence of VX nerve agent use from contaminated white mustard plants. In: Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences . 2014 ; Vol. 470, No. 2168.
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Evidence of VX nerve agent use from contaminated white mustard plants. / Gravett, Matthew R.; Hopkins, Farrha B.; Self, Adam J.; Webb, Andrew J.; Timperley, Christopher M.; Baker, Matthew J.

In: Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences , Vol. 470, No. 2168, 20140076, 08.08.2014.

Research output: Contribution to journalArticle

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