Evaluation of risk factors for postbooster Omicron COVID-19 deaths in England

National Core Studies—Immunology Breakthrough Consortium, Vahé Nafilyan, Isobel L. Ward, Chris Robertson, Aziz Sheikh

Research output: Contribution to journalArticlepeer-review

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With the emergence of the Omicron variant, it has become critical to identify risk factors associated with COVID-19 death in individuals who have completed primary vaccination and received a messenger RNA (mRNA) booster dose. Existing evidence is based on people who have received 1 or 2 doses of a COVID-19 vaccine and were infected by the Alpha or Delta variant.1-3 Understanding which groups are at increased risk of COVID-19 death after receiving a booster is crucial for the prioritization of further booster doses and access to COVID-19 therapeutics.
Original languageEnglish
Article numbere2233446
Number of pages5
JournalJAMA Network Open
Issue number9
Publication statusPublished - 8 Sept 2022


  • England - epidemiology
  • humans
  • risk factors
  • COVID-19


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