@article{9cfb76deca014a50943b2cf72d87cc7c,
title = "Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents, and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy",
abstract = "The slow development of major advances in drug discovery for the treatment of Mycobacterium tuberculosis (Mtb) infection have led to a compelling need for evaluation of more effective drug therapies against tuberculosis. New classes of drugs are constantly being evaluated for anti-mycobacterial activity with currently a very limited number of new drugs approved for TB treatment. Minor Groove Binders (MGBs) have previously revealed promising anti-microbial activity against various infectious agents; however have not yet been screened against Mtb. ",
keywords = "drug discovery, minor groove binder, tuberculosis",
author = "Lerato Hlaka and Michael-Jon Rosslee and Mumin Ozturk and Santosh Kumar and Suraj Parihar and Frank Brombacher and Abedawn Khalaf and Katharine Carter and Fraser Scott and Colin Suckling and Reto Guler",
note = "This is a pre-copyedited, author-produced version of an article accepted for publication in Journal of Antimicrobial Chemotherapy following peer review. The version of record Hlaka, L., Rosslee, M-J., Ozturk, M., Kumar, S., Parihar, S., Brombacher, F., ... Guler, R. (2017). Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents, and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy. Journal of Antimicrobial Chemotherapy, 72(12), 3334–3341, is available online at: https://doi.org/10.1093/jac/dkx326. ",
year = "2017",
month = dec,
day = "1",
doi = "10.1093/jac/dkx326",
language = "English",
volume = "72",
pages = "3334–3341",
journal = "Journal of Antimicrobial Chemotherapy",
issn = "0305-7453",
publisher = "Oxford University Press",
number = "12",
}
