Abstract
Introduction and aim: To evaluate adherence to antihypertensive treatment in rural South Africa and identify potential determinants given concerns with adherence and its impact in this priority disease area. Method: Face-to-face interviews with hypertensive patients and rating their adherence to treatment using defined categorised responses. Associations between adherence and patient characteristics assessed and sensitivity analyses performed. Results: 54.6% of patients were adherent to treatment. Controlled blood pressure (OR = :=2.1; 95% CI [:1.1, -3.8]; p = 0.019), comorbidity (OR = :=2.0; 95% CI [: 1.1, -3.6]; p = 0.032) and smoking (OR = :=0.3; 95% CI [:0.1, -0.8]; p = 0.018) were associated with adherence. Conclusion: Adherence and BP control were suboptimal, only smoking was an independent risk factor for adherence. Adherent patients were twice as likely to have controlled BP, although results were sensitive to the definition of adherence. Initiatives are in place to improve adherence, which will be monitored.
Original language | English |
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Pages (from-to) | 661-672 |
Number of pages | 12 |
Journal | Journal of Comparative Effectiveness Research |
Volume | 7 |
Issue number | 7 |
Early online date | 11 Jun 2018 |
DOIs | |
Publication status | Published - 31 Jul 2018 |
Keywords
- antihypertensive treatment
- rural South Africa
- blood pressure
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Amanj Kurdi
- Strathclyde Institute Of Pharmacy And Biomedical Sciences - Professor
- Health and Wellbeing - Professor
Person: Academic