Abstract
Language | English |
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Pages | 661-672 |
Number of pages | 12 |
Journal | Journal of Comparative Effectiveness Research |
Volume | 7 |
Issue number | 7 |
Early online date | 11 Jun 2018 |
DOIs | |
Publication status | Published - 31 Jul 2018 |
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Keywords
- antihypertensive treatment
- rural South Africa
- blood pressure
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Evaluation of antihypertensive adherence and its determinants at primary health care facilities in rural South Africa. / Rampamba, Enos M; Meyer, Johanna C; Godman, Brian; Kurdi, Amanj; Helberg, Elvera.
In: Journal of Comparative Effectiveness Research, Vol. 7, No. 7, 31.07.2018, p. 661-672.Research output: Contribution to journal › Article
TY - JOUR
T1 - Evaluation of antihypertensive adherence and its determinants at primary health care facilities in rural South Africa
AU - Rampamba, Enos M
AU - Meyer, Johanna C
AU - Godman, Brian
AU - Kurdi, Amanj
AU - Helberg, Elvera
PY - 2018/7/31
Y1 - 2018/7/31
N2 - Introduction and aim: To evaluate adherence to antihypertensive treatment in rural South Africa and identify potential determinants given concerns with adherence and its impact in this priority disease area. Method: Face-to-face interviews with hypertensive patients and rating their adherence to treatment using defined categorised responses. Associations between adherence and patient characteristics assessed and sensitivity analyses performed. Results: 54.6% of patients were adherent to treatment. Controlled blood pressure (OR = :=2.1; 95% CI [:1.1, -3.8]; p = 0.019), comorbidity (OR = :=2.0; 95% CI [: 1.1, -3.6]; p = 0.032) and smoking (OR = :=0.3; 95% CI [:0.1, -0.8]; p = 0.018) were associated with adherence. Conclusion: Adherence and BP control were suboptimal, only smoking was an independent risk factor for adherence. Adherent patients were twice as likely to have controlled BP, although results were sensitive to the definition of adherence. Initiatives are in place to improve adherence, which will be monitored.
AB - Introduction and aim: To evaluate adherence to antihypertensive treatment in rural South Africa and identify potential determinants given concerns with adherence and its impact in this priority disease area. Method: Face-to-face interviews with hypertensive patients and rating their adherence to treatment using defined categorised responses. Associations between adherence and patient characteristics assessed and sensitivity analyses performed. Results: 54.6% of patients were adherent to treatment. Controlled blood pressure (OR = :=2.1; 95% CI [:1.1, -3.8]; p = 0.019), comorbidity (OR = :=2.0; 95% CI [: 1.1, -3.6]; p = 0.032) and smoking (OR = :=0.3; 95% CI [:0.1, -0.8]; p = 0.018) were associated with adherence. Conclusion: Adherence and BP control were suboptimal, only smoking was an independent risk factor for adherence. Adherent patients were twice as likely to have controlled BP, although results were sensitive to the definition of adherence. Initiatives are in place to improve adherence, which will be monitored.
KW - antihypertensive treatment
KW - rural South Africa
KW - blood pressure
UR - https://www.futuremedicine.com/toc/cer/current
U2 - 10.2217/cer-2018-0004
DO - 10.2217/cer-2018-0004
M3 - Article
VL - 7
SP - 661
EP - 672
JO - Journal of Comparative Effectiveness Research
T2 - Journal of Comparative Effectiveness Research
JF - Journal of Comparative Effectiveness Research
SN - 2042-6313
IS - 7
ER -